Evidence map›Paper›PMID 41046048›Full record

ArticleJournal of vascular surgery2026

Textbook outcomes for lower extremity bypass: A useful quality metric for care optimization.

Angela D Sickels, Amanda C Filiberto, Zdenek Novak, Jarrad Rowse, Kimberly Kopecky, Douglas W Jones, Salvatore T Scali, Jesse A Columbo, David H Stone, Adam W Beck

Abstract read
In one paragraph

Article in Journal of vascular surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

10 authors.

Angela D SickelsDivision of Vascular Surgery and Endovascular Therapy, University of Alabama at Birmingham, Birmingham, AL.
Amanda C FilibertoDivision of Vascular Surgery and Endovascular Therapy, University of Alabama at Birmingham, Birmingham, AL.
Zdenek NovakDivision of Vascular Surgery and Endovascular Therapy, University of Alabama at Birmingham, Birmingham, AL.
Jarrad RowseDivision of Vascular Surgery and Endovascular Therapy, University of Alabama at Birmingham, Birmingham, AL.
Kimberly KopeckyDivision of Surgical Oncology, University of Alabama at Birmingham, Birmingham, AL.
Douglas W JonesDivision of Vascular and Endovascular Surgery, University of Massachusetts Memorial Medical Center, Worcester, MA.
Salvatore T ScaliDivision of Vascular Surgery and Endovascular Therapy, University of Florida, Gainesville, FL.
Jesse A ColumboHeart and Vascular Center, Section of Vascular Surgery Dartmouth-Hitchcock Medical Center, Lebanon, NH.
David H StoneHeart and Vascular Center, Section of Vascular Surgery Dartmouth-Hitchcock Medical Center, Lebanon, NH.
Adam W BeckDivision of Vascular Surgery and Endovascular Therapy, University of Alabama at Birmingham, Birmingham, AL. Electronic address: awbeck@uabmc.edu.

Funding

MECHANISMS OF HYPERTENSION AND CARDIOVASCULAR DISEASEST32HL007457 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Martin E Young · 1985 to 2026
$8.6M
Comparative-Effectiveness of Procedures for Carotid RevascularizationK08HL165087 · NHLBI · DARTMOUTH-HITCHCOCK CLINIC · PI Jesse A Columbo · 2023 to 2026
$587k
NHLBI NIH HHS K08 HL165087NHLBI NIH HHS T32 HL007457
6 · The paper itself

Abstract

objectiveTextbook outcomes (TOs) represent the ideal postsurgical scenario that can identify at risk subgroups in need of better follow up. Their application in lower extremity bypass (LEB) has been underexplored. Here, the TO for LEB is defined risk factors identified for failure to achieve a TO.

methodsThe Vascular Quality Initiative was queried for elective LEB cases between 2010 and 2023. A TO was defined as absence of major complications, major adverse limb events, prolonged length of stay (>75th percentile), 30-day mortality, and nonhome discharge. Exclusions were based on pathology, inflow/outflow, conduit, and concomitant operations. Primary outcomes included 1-year survival and failure to achieve a TO. Time-to-event analyses were conducted using the Kaplan-Meier method. Logistic regression was used to identify risk factors for failure to achieve a TO and calculate observed:expected ratios for each center.

resultsOf 49,744 cases analyzed, TOs were achieved in 60.7% (n = 4422), 66.9% (n = 4587), and 60.9% (n = 21,661) of suprainguinal anatomical bypass (SAB), suprainguinal extra-anatomical bypass (EAB), and infrainguinal bypass (IIB), respectively. Kaplan-Meier estimates of 1-year bypass patency and survival were better for TO patients (patency with TO: SAB 99.1%, EAB 98.0%, IIB 93.9% vs non-TO: SAB 97.6%, EAB 96.7%, IIB 89.6%; all log-rank P < .001; survival with TO: SAB 98.6%, EAB 95.6%, IIB 96.1% vs non-TO SAB 90.6%, EAB 83.2%, IIB 85.5%; all log-rank P < .001). Achieving a TO was the strongest independent factor associated with 1-year mortality (SAB: hazard ratio [HR], 0.23; 95% confidence interval [CI], 0.17-0.30; EAB: HR, 0.42, 95% CI, 0.35-0.51; IIB: HR 0.44, 95% CI, 0.40-0.49; all P < .001). Risk factors for failure to achieve a TO among all procedures included non-White race, congestive heart failure, chronic obstructive pulmonary disease, preoperative hemoglobin of <12 g/dL, estimated blood loss of >350 mL, and indication of tissue loss/necrosis (all P < .05). Funnel plot analysis revealed outlier centers for SAB (n = 5), EAB (n = 3), and IIB (n = 22). Comparing individual TO component measures of these centers with national averages identified potential targets (eg, length of stay targets, surgical complication rates) for future quality improvement efforts. Additionally, example centers were identified that could serve as models for improving TO rates at other centers through dissemination of best practices.

conclusionsFailure to achieve a TO is associated with worse long-term LEB outcomes, and these patients may require closer monitoring and support after discharge. TOs are a clinically relevant quality measure that provides a comprehensive framework for identifying areas of improvement in patient care and guiding future quality improvement efforts.

Indexed as

Lower ExtremityPeripheral Arterial DiseaseQuality ImprovementQuality Indicators, Health CareVascular GraftingAgedAged, 80 and overFemaleHumansMaleMiddle AgedPostoperative ComplicationsRetrospective StudiesRisk AssessmentRisk FactorsTime FactorsComposite outcomeLower extremity bypassLower extremity revascularizationQuality improvementTextbook outcome

Identifiers

PMID41046048
PMCPMC12746074

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.