Evidence map›Paper›PMID 41045761›Full record

ArticleBiomaterials2026

Advanced biomechanics and stability of the resin-dentin complex via modular A- and B-type proanthocyanidins.

Mariana Reis-Havlat, Yvette Alania, Shu-Xi Jing, Odair Bim-Junior, Walleska Liberato, Shao-Nong Chen, Guido F Pauli, Ana K Bedran-Russo

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomaterials, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mariana Reis-HavlatDepartment of Oral Biology, College of Dentistry, University of Illinois Chicago, Chicago, IL, 60612, United States; Department of General Dental Sciences, School of Dentistry, Marquette University, Milwaukee, WI, 53233, United States.
Yvette AlaniaDepartment of General Dental Sciences, School of Dentistry, Marquette University, Milwaukee, WI, 53233, United States; Division of Cariology and Operative Dentistry, Department of Comprehensive Dentistry, University of Maryland School of Dentistry, Baltimore, MD, 21201, United States.
Shu-Xi JingPharmacognosy Institute and Department of Pharmaceutical Sciences, Retzky College of Pharmacy, University of Illinois Chicago, Chicago, IL, 60612, United States.
Odair Bim-JuniorDepartment of General Dental Sciences, School of Dentistry, Marquette University, Milwaukee, WI, 53233, United States.
Walleska LiberatoDepartment of Oral Biology, College of Dentistry, University of Illinois Chicago, Chicago, IL, 60612, United States; Department of General Dental Sciences, School of Dentistry, Marquette University, Milwaukee, WI, 53233, United States.
Shao-Nong ChenPharmacognosy Institute and Department of Pharmaceutical Sciences, Retzky College of Pharmacy, University of Illinois Chicago, Chicago, IL, 60612, United States.
Guido F PauliPharmacognosy Institute and Department of Pharmaceutical Sciences, Retzky College of Pharmacy, University of Illinois Chicago, Chicago, IL, 60612, United States.
Ana K Bedran-RussoDepartment of Oral Biology, College of Dentistry, University of Illinois Chicago, Chicago, IL, 60612, United States; Department of General Dental Sciences, School of Dentistry, Marquette University, Milwaukee, WI, 53233, United States. Electronic address: bedran@uic.edu.

Funding

Dentin Biomodification for Optimization of Bioadhesive Dental RestorationsR01DE028194 · NIDCR · UNIVERSITY OF ILLINOIS AT CHICAGO · PI BEDRAN-RUSSO, ANA KARINA B · 2019 to 2023
$2.6M
NIDCR NIH HHS R01 DE028194
6 · The paper itself

Abstract

This study explored the formation and sustainability of the resin-dentin complex optimized by four proanthocyanidins (PACs), modularly defined catechin oligomers with distinct single (B-type) or double (A-type) interflavanyl linkages (IFLs; AA, BB, AAA, BBB). Assessment of their biomimetic potency on the resin-dentin interface [adhesive, hybrid layer (HL), underlying dentin (UD)] involved nano-mechanical dynamic analyses, microtensile bond strength (μTBS), and interfacial micropermeability after 24 h and 6 months in simulated body fluids. The degree of conversion (DC) of PAC-incorporated dental resins was analyzed via ATR-FTIR spectroscopy. Bound and unbound water in dentin were measured using differential scanning calorimetry. Statistical analysis employed ANOVA and post-hoc tests (α = 0.05). A-type PACs increased HL nano-moduli (E'

Indexed as

DentinProanthocyanidinsBiomechanical PhenomenaHumansMaterials TestingSpectroscopy, Fourier Transform InfraredTensile StrengthProanthocyanidinsAdhesionBond strengthCollagen cross linkingDentinModulus mappingNano-mechanical analysisProanthocyanidins

Identifiers

PMID41045761
PMCPMC13358910

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.