Evidence map›Paper›PMID 41045488›Full record

ArticleArchives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists2026

A Guide to the Interpretation and Reliability of Annual Collegiate ImPACT Baselines by Sex.

Kristen G Quigley, Brian Szekely, Madison Fenner, Philip Pavilionis, Nicholas G Murray

Abstract read
In one paragraph

Article in Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Kristen G QuigleyDepartment of Kinesiology, School of Public Health, University of Nevada, 1664 N. Virginia Street m/s 0274, Reno, NV 89557, USA.ORCID 0000-0002-3299-7664
Brian SzekelyDepartment of Rehabilitation Medicine, New York University Grossman School of Medicine, 550 1st Ave, New York, NY 10016, USA.
Madison FennerDepartment of Kinesiology, School of Public Health, University of Nevada, 1664 N. Virginia Street m/s 0274, Reno, NV 89557, USA.
Philip PavilionisDepartment of Kinesiology, School of Public Health, University of Nevada, 1664 N. Virginia Street m/s 0274, Reno, NV 89557, USA.
Nicholas G MurrayDepartment of Kinesiology, School of Public Health, University of Nevada, 1664 N. Virginia Street m/s 0274, Reno, NV 89557, USA.

Funding

Tracking and EvaluationU54GM104944 · NIGMS · UNIVERSITY OF NEVADA LAS VEGAS · PI MARCHAND, GWEN · 2013 to 2023
$39.6M
NIGMS NIH HHS U54 GM104944NIH HHS 1U54GM104944NIH HHS P30GM145645
6 · The paper itself

Abstract

objectiveTo create a sex-specific clinicians guide to evaluating significant immediate post-concussion assessment and cognitive testing (ImPACT) score changes using minimal detectable change (MDC) ranges, to evaluate the sex-specific test-retest reliability using intraclass correlation coefficients (ICCs), and to compare male and female performance across all composite and subtest scores.

methodData from 390 National Collegiate Athletic Association Division I athletes (n = 390; male = 106, female = 284) across four athletic seasons (2020-2021 through 2024-2025) who had completed ImPACT remotely for two consecutive seasons were used to calculate the MDC and ICC at the 95% confidence intervals (CIs) by sex, as well as to compare sex-based performance for all ImPACT scores (subtest and composite).

resultsThe visual memory composite score, as well as the subtests of design memory correct distractors (immediate), design memory hits (delay), XO total correct memory, XO total correct (interference), XO average correct reaction time (RT; interference), symbol match total correct RT (visible), and color match total correct, exhibited significant differences between males and females at the first and/or second remote time point. ICCs for females demonstrated poor reliability on 14 of the 33 subtest scores (ICC = 0.06-0.49) and on the visual memory composite score (ICC = 0.49). For males, 11 of the 33 subtests had poor reliability (ICC = 0.21-0.48). Many of the subtests present poor reliability for both genders, particularly as it relates to the three letters task.

conclusionsThis study found sex differences on ImPACT performance, suggesting that sex-specific MDC values are needed to evaluate significant changes in ImPACT scores. Additionally, this study found several ImPACT subtest scores to be unreliable, suggesting only moderate to good scores be used in clinical evaluation.

Indexed as

Athletic InjuriesBrain ConcussionNeuropsychological TestsAdolescentAthletesFemaleHumansMaleReproducibility of ResultsSex FactorsUniversitiesYoung AdultGender effectsHead injuryMild cognitive impairmentTest constructionTraumatic brain injury

Identifiers

PMID41045488
PMCPMC12857202

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.