Evidence map›Paper›PMID 41045395›Full record

ArticleClinical autonomic research : official journal of the Clinical Autonomic Research Society2026

Vestibulo-sympathetic interaction and otolith function in postural orthostatic tachycardia syndrome.

Tonghoon Woo, Yukang Kim, Jueun Kim, Jin-Woo Park, Sun-Uk Lee, Euyhyun Park, Gerard J Kim, Byung-Jo Kim, Ji-Soo Kim

Abstract read
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In one paragraph

Article in Clinical autonomic research : official journal of the Clinical Autonomic Research Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Correlation of utricular function with elevated ambulatory heart rate in postural orthostatic tachycardia syndrome.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Tonghoon WooNeurotology and Neuro-Ophthalmology Laboratory, Korea University Medical Center, Seoul, South Korea.
Yukang KimNeurotology and Neuro-Ophthalmology Laboratory, Korea University Medical Center, Seoul, South Korea.
Jueun KimNeurotology and Neuro-Ophthalmology Laboratory, Korea University Medical Center, Seoul, South Korea.
Jin-Woo ParkDepartment of Neurology, Korea University Medical Center, 73 Goryeodae-ro, Seongbuk-gu, Seoul, 02841, South Korea.
Sun-Uk LeeNeurotology and Neuro-Ophthalmology Laboratory, Korea University Medical Center, Seoul, South Korea. sulee716@gmail.com.ORCID http://orcid.org/0000-0001-8660-7759
Euyhyun ParkNeurotology and Neuro-Ophthalmology Laboratory, Korea University Medical Center, Seoul, South Korea.
Gerard J KimDepartment of Computer Science and Engineering, Korea University, Seoul, South Korea.
Byung-Jo KimDepartment of Neurology, Korea University Medical Center, 73 Goryeodae-ro, Seongbuk-gu, Seoul, 02841, South Korea.
Ji-Soo KimDizziness Center, Clinical Neuroscience Center, Seoul National University Bundang Hospital, Seongnam, South Korea.

Funding

Korea University Anam Hospital O2514421Ministry of Health and Welfare HI14C3477Ministry of Science and ICT, South Korea RS-2025-00515755
6 · The paper itself

Abstract

BACKGROUND AND

objectiveThe association between blood pressure variability (BPV) or heart rate variability (HRV) and the baroreflex is well established. However, the role of the vestibular-autonomic reflex in regulating BP and HR stability has primarily been explored only in experimental studies. We aimed to delineate the association of BPV and HRV with otolith function in postural orthostatic tachycardia syndrome (POTS).

methodsWe retrospectively analyzed data from consecutive patients with POTS recruited between April 2021 and April 2025 at a tertiary referral-based hospital in South Korea. All patients underwent a head-up tilt table test using a Finometer

resultsA total of 47 patients with POTS (mean age

conclusionsOtolithic function may play a role in accentuating BPV and HRV in POTS by contributing to enhanced sympathetic outflow.

Indexed as

Otolithic MembranePostural Orthostatic Tachycardia SyndromeSympathetic Nervous SystemVestibular Evoked Myogenic PotentialsAdultBaroreflexBlood PressureFemaleHeart RateHumansMaleMiddle AgedRetrospective StudiesTilt-Table TestYoung AdultAutonomic nervous systemBlood pressure variabilityHeart rate variabilityOtolithPostural orthostatic tachycardia syndrome

Identifiers

PMID41045395

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.