ArticleMikrochimica acta2025
Electrophoresis-based electrochemical sensor for rapid detection of sialic acid in human serum.
Article in Mikrochimica acta, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
Abstract
A novel electrochemical sensor is introduced that significantly accelerates sialic acid (SA) detection by utilizing an electrophoresis device, which reduces the binding time from 20 to 5 min. The results indicate that the current signal change (ΔI) of the sensor is more than twofold higher than that of conventional sensors after 5 min. Furthermore, to enhance the intensity of the sensor's signal and simplify the operational procedure, we employed a method that electrochemically reduces graphene oxide/3-aminophenylboronic acid (GO/APBA) to reduced graphene oxide/3-aminophenylboronic acid (rGO/APBA) in a single step. This reduction process effectively removes some oxygen groups from GO, further enhancing the current signal. The linear detection range for SA was between 0.1 mM and 3 mM, with a detection limit of 0.084 mM (S/N = 3). Notably, the electrophoresis-enhanced sensor can successfully detect SA in actual human serum samples. Overall, this sensor represents a significant advancement in the electrochemical sensing of SA, providing a rapid, selective, and cost-effective approach for developing electric field-enhanced detection technologies.
Indexed as
Identifiers
41045379What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.