Evidence map›Paper›PMID 41045298›Full record

ArticleWorld journal of urology2025

Beyond the sheath: unmasking true predictors of Post-fURS fever through propensitymatched precision.

Peng Zhu, Xi Hua, Xiang Teng, Rong Wang

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Article in World journal of urology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Peng Zhu *Department of Urology, Jiangdu People's Hospital Affiliated to Yangzhou University, Yangzhou, Jiangsu, China.
Xi Hua *Department of Nephrology, Affiliated Hospital of Yangzhou University, Yangzhou, Jiangsu, China.
Xiang TengDepartment of Urology, Jiangdu People's Hospital Affiliated to Yangzhou University, Yangzhou, Jiangsu, China.
Rong WangDepartment of Urology, Jiangdu People's Hospital Affiliated to Yangzhou University, Yangzhou, Jiangsu, China. wangrong2024@suda.edu.cn.ORCID http://orcid.org/0009-0004-0911-4589

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimFlexible ureteroscopy (fURS) is a prevalent minimally invasive treatment for upper urinary tract stones, but postoperative fever remains a considerable concern. The precise role of ureteral access sheath (UAS) utilization in influencing infectious complications following fURS continues to be debated. This study aimed to comprehensively evaluate the perioperative and postoperative outcomes of fURS, with a specific focus on the influence of UAS utilization. Furthermore, we sought to identify independent predictive factors for the development of postoperative fever after fURS, utilizing a propensity score-matched analysis to mitigate confounding variables and enhance the robustness of our findings.

methodsThis retrospective cohort study analyzed 486 patients undergoing fURS, with propensity score matching (PSM) used to create balanced UAS (n = 150) and non-UAS (n = 150) groups. Perioperative outcomes and predictors of postoperative fever (defined as ≥ 37.5 °C within 48 h) were evaluated using univariate, multivariate logistic regression, and receiver operating characteristic (ROC) curve analyses.

resultsPostoperative fever rates were comparable between UAS and non-UAS groups (12% vs. 9.3%, p = 0.454), although UAS use was associated with significantly longer hospital stays (median 5 vs. 4 days, p = 0.003). Independent predictors of postoperative fever included positive preoperative urine culture [adjusted odds ratio (aOR) 7.535, 95% CI 2.681-21.175, p < 0.001], elevated postoperative C-reactive protein (CRP) (aOR: 1.211, 95% CI 1.093-1.343, p < 0.001), and increased postoperative white blood cell (WBC) count (aOR: 1.200, 95% CI 1.012-1.424, p = 0.036). ROC analysis demonstrated high predictive accuracy for postoperative CRP (AUC: 0.943) and a combined prediction model (AUC: 0.951).

conclusionsPerforming fURS without UAS did not significantly increase the risk of postoperative fever, supporting its safety in carefully selected cases. Monitoring preoperative urine culture results and postoperative CRP and WBC levels are critical for the early prediction and timely intervention of postoperative fever.

Indexed as

FeverKidney CalculiPostoperative ComplicationsUreteral CalculiUreteroscopesUreteroscopyAdultAgedFemaleHumansMaleMiddle AgedPropensity ScoreRetrospective StudiesFlexible ureteroscopyInflammatory markersPostoperative feverPropensity score matchingUreteral access sheathUrinary tract infection

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.