Evidence map›Paper›PMID 41045033›Full record

ReviewTherapeutic delivery2025

Harnessing nanoparticles for phytochemical delivery: a comprehensive review of safety and therapeutic potential.

Sharon Oladipupo, Damilare Emmanuel Rotimi, Emmanuel Henry Ezenabor, Adebola Busola Ojo, Oluwatomisin Aderonke Akinsola, Oluwafemi Adeleke Ojo

Abstract readReview
In one paragraph

Review in Therapeutic delivery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Bridging bioactive metabolites ofFrontiers in pharmacology · 2026
    Review
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sharon OladipupoChemistry and Industrial Chemistry Programme, Bowen University, Iwo, Nigeria.
Damilare Emmanuel RotimiDepartment of Biochemistry, Landmark University, Omu-Aran, Nigeria.
Emmanuel Henry EzenaborBiochemistry Programme, Bowen University, Iwo, Nigeria.
Adebola Busola OjoDepartment of Environmental Management and Toxicology, University of Ilesa, Ilesa, Nigeria.
Oluwatomisin Aderonke AkinsolaMicrobiology Programme, Bowen University, Iwo, Nigeria.
Oluwafemi Adeleke OjoResearch Centre for Integrative Physiology and Pharmacology, Institute of Biomedicine, University of Turku, Turku, Finland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nanoparticle encapsulation has emerged as a relevant technology with the potential to revolutionize multiple fields, including medicine, food technology, cosmetics, and environmental monitoring. This review discusses the fundamental aspects of nanoparticle encapsulation, highlighting its benefits, such as enhanced solubility, stability, and bioavailability of phytochemicals. The data for this report were obtained via an extensive review of the peer-reviewed scientific literature. We reviewed various types of nanoparticles used in encapsulation, the efficacy of nanoparticle-encapsulated phytochemicals, and the challenges faced, including formulation complexity and regulatory hurdles. The review also considers current and future applications, providing examples of how advanced technologies such as artificial intelligence and novel manufacturing methods contribute to innovation in this field. As nanoparticle technology progresses, addressing safety and regulatory issues will be critical for its successful integration and commercialization. This review underscores the promising future of nanoparticle technology.

Indexed as

Drug Delivery SystemsNanoparticle Drug Delivery SystemNanoparticlesPhytochemicalsAnimalsBiological AvailabilityDrug CompoundingHumansSolubilityNanoparticle Drug Delivery SystemPhytochemicalsencapsulationNanoparticlesphytochemicalstoxicity

Identifiers

PMID41045033
PMCPMC12694916

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.