ArticleJournal of health psychology2026
Psychosocial risk and protective factors for men's lower urinary tract symptoms: A secondary analysis of CARDIA cohort study data.
Sonya S Brady, Andrés Arguedas, Jared D Huling, Gerhard Hellemann, Cora E Lewis, David R Jacobs, Pamela J Schreiner, Cynthia S Fok, Stephen K Van Den Eeden, Alayne D Markland
Abstract read
In one paragraphArticle in Journal of health psychology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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What it found
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2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
10 authors.
Andrés ArguedasUniversity of Minnesota School of Public Health, Minneapolis, MN, USA.
Jared D HulingUniversity of Minnesota School of Public Health, Minneapolis, MN, USA.
Gerhard HellemannUniversity of Alabama at Birmingham School of Public Health, Birmingham, AL, USA.
David R JacobsUniversity of Minnesota School of Public Health, Minneapolis, MN, USA.
Pamela J SchreinerUniversity of Minnesota School of Public Health, Minneapolis, MN, USA.
Cynthia S FokUniversity of Minnesota Medical School, Minneapolis, MN, USA.
Stephen K Van Den EedenKaiser Permanente Northern California, Oakland, CA, USA.
Alayne D MarklandUniversity of Alabama at Birmingham and Birmingham VA Medical Center, AL, USA.
Funding
CORONARY ARTERY RISK DEVELOPMENT IN YOUNG ADULTS (CARDIA) STUDY - COORDINATING CENTER (CC)75N92023D00002 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI LI, JING · 2023 to 2025
$6.8MCARDIA-PLUS: A Life Course Investigation of Biopsychosocial Pathways to Bladder Health and Lower Urinary Tract SymptomsR01DK125274 · NIDDK · UNIVERSITY OF MINNESOTA · PI BRADY, SONYA S, MARKLAND, ALAYNE DENISE · 2021 to 2024
$2.5MAdult Life Predictors of Genitourinary DisordersR01DK084997 · NIDDK · KAISER FOUNDATION RESEARCH INSTITUTE · PI VAN DEN EEDEN, STEPHEN K. · 2010 to 2014
$2.4MCORONARY ARTERY RISK DEVELOPMENT IN YOUNG ADULTS (CARDIA) STUDY - OAKLAND FIELD CENTER75N92023D00003 · NHLBI · KAISER FOUNDATION RESEARCH INSTITUTE · PI BHATT, ANKEET S. · 2023 to 2025
$2.2MCORONARY ARTERY RISK DEVELOPMENT IN YOUNG ADULTS (CARDIA) STUDY - BIRMINGHAM FIELD CENTER75N92023D00005 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI LEWIS, CORA · 2023 to 2025
$2.2MCORONARY ARTERY RISK DEVELOPMENT IN YOUNG ADULTS (CARDIA) STUDY - CHICAGO FIELD CENTERDIVERSITY SUPPLEMENT FOR MORGANN WEST75N92023D00004 · NHLBI · NORTHWESTERN UNIVERSITY · PI CARNETHON, MERCEDES · 2023 to 2025
$2.1MCORONARY ARTERY RISK DEVELOPMENT IN YOUNG ADULTS (CARDIA) STUDY - UNIVERSITY OF MINNESOTA FIELD CENTER.75N92023D00006 · NHLBI · UNIVERSITY OF MINNESOTA · PI SCHREINER, PAMELA J · 2023 to 2025
$1.7MResearch and Mentoring Program in Improving Access to Incontinence Care for Older AdultsK24AG073586 · NIA · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI Alayne Denise Markland · 2022 to 2026
$619kNHLBI NIH HHS 75N92023D00002NHLBI NIH HHS 75N92023D00003NHLBI NIH HHS 75N92023D00004NHLBI NIH HHS 75N92023D00005NHLBI NIH HHS 75N92023D00006NIA NIH HHS K24 AG073586NIDDK NIH HHS R01 DK084997NIDDK NIH HHS R01 DK125274
6 · The paper itselfAbstract
This study is a secondary analysis of Coronary Artery Risk Development in Young Adults data examining whether men's experience of psychosocial factors from baseline (1985-1986), when men were aged 18-30 years, through 25 years of follow-up (2010-2011) are associated with lower urinary tract symptoms (LUTS) in 2012-2013. Consistent with previous literature, adverse childhood family environment (OR = 1.24, 95% CI 1.07, 1.43) and depressive symptoms across early and midlife adulthood (OR = 1.60, 95% CI 1.38, 1.87) were associated with higher numbers of and more severe LUTS, a composite measure. Novel findings demonstrated that interpersonal stressors (OR = 1.24, 95% CI 1.07, 1.44) and other life stressors (OR = 1.33, 95% CI 1.15, 1.53) in early and midlife adulthood were associated with worse LUTS among men, while emotional support was protective (OR = 0.69, 95% CI 0.60, 0.81). Findings suggest that a variety of psychosocial experiences may influence LUTS. Additional research is needed to confirm novel findings and identify mechanisms by which life course psychosocial factors may influence the development, maintenance, or worsening of LUTS.
Indexed as
Lower Urinary Tract SymptomsSocial SupportStress, PsychologicalAdolescentAdultCohort StudiesDepressionHumansMaleProtective FactorsRisk FactorsYoung Adultadverse childhood experiencesbladder healthdepressive symptomslower urinary tract symptomsLUTSmensocial networkssocial supportstressors
Identifiers
PMID41044851
PMCPMC12517055
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