Evidence map›Paper›PMID 41044807›Full record

ArticleAnnals of dermatology2025

Differential Modulation of Skin Barrier Proteins and Lipid Synthesis by

Haivin Kim, Aram Kim, Hanyoung Kim, Dahye Seo, Suji Son, DongHyun Kim, Jung U Shin

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Annals of dermatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Haivin Kim *Department of Biomedical Science, CHA University, Seongnam, Korea.ORCID https://orcid.org/0009-0000-0972-3000
Aram Kim *Department of Biomedical Science, CHA University, Seongnam, Korea.ORCID https://orcid.org/0000-0002-5458-1985
Hanyoung KimCentral Research Laboratories, Aekyung Co., Ltd., Daejeon, Korea.ORCID https://orcid.org/0009-0009-4853-2878
Dahye SeoDepartment of Biomedical Science, CHA University, Seongnam, Korea.ORCID https://orcid.org/0009-0007-3919-6011
Suji SonDepartment of Biomedical Science, CHA University, Seongnam, Korea.ORCID https://orcid.org/0000-0001-7218-9330
DongHyun KimDepartment of Dermatology, CHA Bundang Medical Center, CHA University School of Medicine, Seongnam, Korea.ORCID https://orcid.org/0000-0003-3394-2400
Jung U ShinDepartment of Dermatology, CHA Bundang Medical Center, CHA University School of Medicine, Seongnam, Korea. likesomeone@cha.ac.kr.ORCID https://orcid.org/0000-0001-5259-6879

Funding

Aekyung Co., Ltd. RND2023-103Ministry of Health and Welfare RS-2023-KH140992
6 · The paper itself

Abstract

backgroundThe skin microbiome plays a critical role in regulating epidermal differentiation and immune responses. Understanding of how individual microbial species influence the expression of barrier proteins and lipid synthesis pathways is essential for elucidating their contributions to skin barrier function.

objectiveThis study aimed to investigate the distinct effects of

methodsKeratinocyte 2-dimensional monolayer cultures and self-assembled 3-dimensional skin models were treated with

results

conclusionCollectively, these findings suggest that

Indexed as

In vitro 3D modelKeratinocytesLipidsSkin barrier functionSkin microbiome

Identifiers

PMID41044807
PMCPMC12505365

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.