Evidence map›Paper›PMID 41044755›Full record

ArticleBMC surgery2025

Endoscopic purse-string suture technique for postoperative drain-related leakage management in gastrointestinal surgery.

Guangxu Zhu, Lingai Kong, Xiuwen Liu, Shengjie Zhou, Shunyao Song, Baoqiang Shan, Youchao Xu, Qihang Sun, Xuren Lu, Qingshun Zhu and 4 more

Abstract read
In one paragraph

Article in BMC surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Guangxu ZhuWeifang People's Hospital, Weifang, Shandong, China.
Lingai KongWeifang People's Hospital, Weifang, Shandong, China.
Xiuwen LiuWeifang People's Hospital, Weifang, Shandong, China.
Shengjie ZhouWeifang People's Hospital, Weifang, Shandong, China.
Shunyao SongWeifang People's Hospital, Weifang, Shandong, China.
Baoqiang ShanWeifang People's Hospital, Weifang, Shandong, China.
Youchao XuWeifang People's Hospital, Weifang, Shandong, China.
Qihang SunSchool of Clinical Medicine, Shandong Second Medical University, Weifang, China.
Xuren LuSchool of Clinical Medicine, Shandong Second Medical University, Weifang, China.
Qingshun ZhuWeifang People's Hospital, Weifang, Shandong, China.
Bing JiangWeifang People's Hospital, Weifang, Shandong, China.
Cai XuWeifang People's Hospital, Weifang, Shandong, China.
Honglei GaoWeifang People's Hospital, Weifang, Shandong, China. leier870627@163.com.
Jianjun QuWeifang People's Hospital, Weifang, Shandong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAbdominal drain-associated fistulas (ADAFs) represent severe complications following gastrointestinal surgery, where conventional surgical reintervention carries invasiveness risks and extended recovery periods. This study evaluates the clinical efficacy and safety of endoscopic purse-string suturing for managing ADAFs.

methodsA retrospective cohort analysis included 41 patients with postoperative ADAFs treated at Shandong Second Medical University and external referral centers between January 2015 and June 2024.

resultsEndoscopic intervention achieved technical success in 87.8% (36/41) of cases, with clinical success observed in 63.4% (26/41). Subgroup analysis demonstrated significantly superior clinical outcomes in isolated ADAFs versus cases involving concurrent anastomotic disruption (90.0% vs. 39.1%, P = 0.001). Multivariate regression identified two independent predictors of reduced therapeutic efficacy: preoperative anastomotic stenosis (OR = 0.083, P = 0.041) and fistulous orifice diameter > 1 cm (OR = 0.039, P = 0.004). During 12-month follow-up, no mortality or fistula recurrence occurred. Postprocedural anastomotic stenosis developed in 4.9% (2/41) of patients, successfully managed through endoscopic balloon dilation (n = 1) and gastrointestinal stent placement (n = 1).

conclusionEndoscopic purse-string suturing emerges as a minimally invasive, safe, and effective therapeutic strategy for ADAFs, particularly demonstrating optimal clinical performance in isolated drain-associated fistulas with orifices ≤ 1 cm diameter.

Indexed as

Anastomotic LeakDigestive System Surgical ProceduresDrainageEndoscopy, GastrointestinalPostoperative ComplicationsSuture TechniquesAdultAgedFemaleHumansMaleMiddle AgedRetrospective StudiesTreatment OutcomeAnastomotic leakageEndoscopic interventionGastrointestinal surgeryPurse-string suturing

Identifiers

PMID41044755
PMCPMC12495736

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.