ArticleThrombosis journal2025
The influence factors on the resolution of pulmonary embolism by CT pulmonary angiography.
Article in Thrombosis journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06073366 (Long-term Surveillance of Patients With Venous Thromboembolism), which is not on this map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Long-term Surveillance of Patients With Venous Thromboembolism: a Nationwide Prospective Cohort Study
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9 authors.
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Abstract
objectiveResidual chronic obstruction of Pulmonary Embolism (PE) can contribute to pulmonary hypertension and persistent cardiopulmonary limitations. This study comprehensively investigates the influence factors on the resolution of PE clots by CT pulmonary angiography (CTPA).
methodsA retrospective analysis of 102 patients with acute PE diagnosed by CTPA was conducted based on a registered prospective PE cohort (NCT06073366). Follow-up CTPA studies (3 to 6 months post-diagnosis) were analyzed for the rate of improvement and the complete resolution rate of PE clots. Univariate analyses were performed using chi-square tests, and multivariate logistic regression was applied to adjust for confounding factors.
resultsA total of 2,958 vessels from 102 participants were analyzed, 219 were completely obstructed, and 1439 were partially obstructed. We did not identify any factors that had a significant effect on the rate of improvement. The complete resolution rate of PE clots was lower in completely obstructed vessels compared to partially obstructed vessels, and they had a 110% higher risk of residual thrombus (OR: 2.10, 95% CI: 1.46–2.98, p < 0.001). The rate of complete resolution of PE clot remained lower in accepting thrombolytic than in accepting anticoagulation (OR: 2.01, 95% CI: 1.14–3.77, p < 0.001). However, there was no significant difference in the effect of risk stratification of PE, location of clots (central clots only Vs central and peripheral clots Vs peripheral clots only), elderly, sex, obesity, and comorbid deep venous thrombosis on the complete resolution rate of PE clots.
conclusionPatients with completely obstructed PE had a higher risk of residual thrombus than those with partially obstructed through medical therapy. The study highlights that after receiving medical therapy, patients with PE who have complete obstruction could require further exploration of treatment strategies for residual thrombus.
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