Evidence map›Paper›PMID 41044619›Full record

Trial reportJournal of neuroengineering and rehabilitation2025

Safety and efficacy of add-on robotic therapy for early mobilization in intermediate neurocritical care: a pilot study.

Ann-Kathrin Joerger, Kim K Peper, Elisabeth R Jensen, Maria Wostrack, Benedikt Etzig, Nicole Lange, Barbara Vogel, Alexander Koenig, Sami Haddadin, Bernhard Meyer

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of neuroengineering and rehabilitation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ann-Kathrin JoergerDepartment of Neurosurgery, Technical University of Munich, TUM University Hospital Rechts der Isar, Ismaningerstr. 22, 81675, Munich, Germany. annkathrin.joerger@tum.de.
Kim K PeperMunich Institute of Robotics and Machine Intelligence, Technical University of Munich, Georg-Brauchle-Ring 60, 80992, Munich, Germany.
Elisabeth R JensenMunich Institute of Robotics and Machine Intelligence, Technical University of Munich, Georg-Brauchle-Ring 60, 80992, Munich, Germany.
Maria WostrackDepartment of Neurosurgery, Technical University of Munich, TUM University Hospital Rechts der Isar, Ismaningerstr. 22, 81675, Munich, Germany.
Benedikt EtzigDepartment of Neurosurgery, Technical University of Munich, TUM University Hospital Rechts der Isar, Ismaningerstr. 22, 81675, Munich, Germany.
Nicole LangeDepartment of Neurosurgery, Technical University of Munich, TUM University Hospital Rechts der Isar, Ismaningerstr. 22, 81675, Munich, Germany.
Barbara VogelDepartment of Orthopaedics and Sportorthopaedics, Department of Physiotherapy, Technical University of Munich, TUM University Hospital Rechts der Isar, Ismaningerstr. 22, 81675, Munich, Germany.
Alexander KoenigMunich Institute of Robotics and Machine Intelligence, Technical University of Munich, Georg-Brauchle-Ring 60, 80992, Munich, Germany.
Sami HaddadinMunich Institute of Robotics and Machine Intelligence, Technical University of Munich, Georg-Brauchle-Ring 60, 80992, Munich, Germany.
Bernhard MeyerDepartment of Neurosurgery, Technical University of Munich, TUM University Hospital Rechts der Isar, Ismaningerstr. 22, 81675, Munich, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEarly mobilization has become a cornerstone of critical care due to its benefits in mitigating adverse effects associated with prolonged immobility. Individuals with critical neurosurgical conditions face unique challenges for mobilization, including paresis, cognitive dysfunction, and reliance on cerebral monitoring devices. Staffing limitations, high workloads, and person-specific factors further hinder early mobilization. In recent decades, robots have been developed to overcome these barriers. This pilot study aims to evaluate the safety and efficacy of using the VEMOTION

methodsA randomized controlled pilot study was conducted at a tertiary hospital involving 18 individuals who required intermediate care due to severe neurosurgical conditions. Participants in the control group received standard physiotherapy, while those in the study group received VEMOTION

resultsNo AEs or SAEs were observed in either group related to the therapy. The study group showed greater improvements in the CPAx, with a median increase of 15 (IQR 11-19) points, compared to a median increase of 4 (IQR: 0-5) points in the control group (p = 0.0002). In the control group, the median score of the individual items of the CPAx did not change significantly over the course of the therapy, whereas in the study group, the median of each individual item significantly improved over time.

conclusionsThe results of this pilot study indicate that VEMOTION

Indexed as

Critical CareEarly AmbulationPhysical Therapy ModalitiesRoboticsAdultAgedFemaleHumansMaleMiddle AgedPilot ProjectsTreatment OutcomeCritical care physiotherapyEarly mobilizationRobotic mobilization therapy

Identifiers

PMID41044619
PMCPMC12492941

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.