Evidence map›Paper›PMID 41044571›Full record

ArticleCardiovascular diabetology2025

Development and evaluation of a machine learning prediction model for short-term mortality in patients with diabetes or hyperglycemia at emergency department admission.

Per Wändell, Marcelina Wierzbicka, Karolina Sigurdsson, Anna Olofsson, Caroline Wachtler, Torgny Wessman, Olle Melander, Ulf Ekelund, Anders Björkelund, Axel C Carlsson and 1 more

Abstract readMulticenter Study
In one paragraph

Article in Cardiovascular diabetology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Per WändellDepartment of Neurobiology, Care Sciences and Society, Division of Family Medicine and Primary Care, Karolinska Institutet, Huddinge, Sweden. per.wandell@ki.se.
Marcelina WierzbickaDepartment of Emergency and Internal Medicine, Skånes University Hospital, Malmö, Sweden.
Karolina SigurdssonDepartment of Emergency and Internal Medicine, Skånes University Hospital, Malmö, Sweden.
Anna OlofssonDivision of Biostatistics, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Caroline WachtlerDepartment of Neurobiology, Care Sciences and Society, Division of Family Medicine and Primary Care, Karolinska Institutet, Huddinge, Sweden.
Torgny WessmanDepartment of Emergency and Internal Medicine, Skånes University Hospital, Malmö, Sweden.
Olle MelanderDepartment of Emergency and Internal Medicine, Skånes University Hospital, Malmö, Sweden.
Ulf EkelundEmergency medicine, Department of Clinical Sciences Lund, Department of Emergency Medicine, Skåne University Hospital, Lund University, Lund, Sweden.
Anders BjörkelundCentre for Environmental and Climate Science, Lund University, Lund, Sweden.
Axel C Carlsson *Department of Neurobiology, Care Sciences and Society, Division of Family Medicine and Primary Care, Karolinska Institutet, Huddinge, Sweden.
Toralph Ruge *Department of Emergency and Internal Medicine, Skånes University Hospital, Malmö, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPatients with diabetes admitted to emergency care face a higher risk of complications, including prolonged hospital stays, admissions to the intensive care unit and mortality.

aimTo develop a machine learning (ML) model to predict 30-day mortality in patients with diabetes admitted to the emergency department (ED). DESIGN AND

settingA cohort study utilizing data from all nine ED's in Region Skåne 2017 to 2018. Totally 74,611 patient visits, representing 34,280 unique patients aged > 18 years with diabetes or hyperglycemia (glucose were > 11 mmol/L). The analysis focused on four groups, men and women aged 40-69 and ≥ 70 years.

methodsStochastic gradient boosting was employed to develop a model predicting 30-day mortality. Variable importance was assessed using normalized relative influence (NRI) scores. Variables in certain hospitals were used to train the models, and the models were tested in other hospitals.

resultsKey predictors included laboratory values (pH, base excess, pCO

conclusionsA machine learning model based on routinely collected data in the ED accurately predicted 30-day mortality with high specificity and sensitivity. This approach shows promise in identifying high-risk patients requiring close monitoring and timely interventions.

Indexed as

Blood GlucoseDecision Support TechniquesDiabetes MellitusEmergency Service, HospitalHospital MortalityHyperglycemiaMachine LearningPatient AdmissionAdultAgedBiomarkersFemaleHumansMaleMiddle AgedPredictive Value of TestsBiomarkersBlood GlucoseArtificial intelligenceDiabetesEmergency medicineGradient boostingNormalized relative influencePrediction

Identifiers

PMID41044571
PMCPMC12492943

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.