Evidence map›Paper›PMID 41044504›Full record

SynthesisBMC public health2025

Predictors and prevalence of perinatal mortality in Ghana: a systematic review and meta-analysis.

Damien Punguyire, Munawar Harun Koray, Gilbert Abotisem Abiiro

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Damien PunguyireUpper West Regional Health Directorate, Ghana Health Service, Wa, Upper West Region, Ghana.
Munawar Harun KorayUpper West Regional Health Directorate, Ghana Health Service, Wa, Upper West Region, Ghana. gbanglin@rocketmail.com.
Gilbert Abotisem AbiiroDepartment of Health Services, Policy, Planning, Management and Economics, University for Development Studies, Tamale, Northern Region, Ghana.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGhana has consistently reported a high perinatal mortality rate. This has raised concerns regarding the country's ability to achieve the Sustainable Development Goals 3 target 2 by 2030. This comprehensive review presents the pooled prevalence and predictors of perinatal mortalities in Ghana guided by the Anderson's framework of healthcare utilization.

methodsA comprehensive literature search was conducted mainly from four electronic databases; PubMed, Web of Science, Scopus and CINAHL as they collectively index > 90% of relevant maternal health journals in Africa and also eases the burden of screening. Eligible studies, published from 1st January 2010 to 30th June, 2024, were charted and synthesized, with focus on the three primary domains of Anderson's framework: pre-disposing factors, enabling factors and need factors. Meta-analysis was conducted to estimate the pooled prevalence of perinatal mortality rate within each of the sub-regions. Significant heterogeneity was detected among the various surveys (I2 > 50%), hence a random effect model was reported. Sub-group and meta-regression were performed to identify the sources of heterogeneity observed in the study.

resultsA total of 2,184 articles were initially identified for review, but after multiple rounds of screening and deduplication, only 30 full-text articles were finally included. The most frequent study design was cross-sectional, accounting for 23.3% of the studies. The Pooled estimate of perinatal mortality is 44.8 (95%CI: 15.4-74.2) per 1000 births in Ghana, with very high heterogeneity (I

conclusionThis review presents the complex interplay of factors determining perinatal mortality in Ghana. In addition to the predictors identified, the review reveals gaps in literature particularly the lack of case-control studies in rural settings and inadequate focus on healthcare quality, socio-economic influences, and policy impacts. Future studies should address these gaps using a holistic approach that takes into account Ghana's diverse social and geographical factors to better reduce perinatal mortality. SYSTEMATIC REVIEW REGISTRATION: The review protocol was registered in PROSPERO (CRD42024564968).

Indexed as

Perinatal MortalityFemaleGhanaHumansInfant, NewbornPregnancyPrevalenceRisk FactorsEarly neonatal deathGhanaPerinatal mortalityPredictorsStillbirth

Identifiers

PMID41044504
PMCPMC12495840

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.