ReviewBMC pregnancy and childbirth2025
Right ventricular outflow tract obstruction in recipient twins of twin-to-twin transfusion syndrome: 13 years of single-center data and literature review.
Review in BMC pregnancy and childbirth, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Twin-to-twin transfusion syndrome: from pathophysiology to long-term outcome-a narrative review.European journal of pediatrics · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo investigate the characteristics of right ventricular outflow tract obstruction (RVOTO) in recipient twins of twin-to-twin transfusion syndrome (TTTS), including its prevalence, perinatal outcomes, and the impact of fetoscopic laser coagulation (FLC) on postnatal RVOTO status.
methodsThis retrospective study included recipient twins of TTTS treated with FLC at the Asan Medical Center between January 2011 and December 2023. Among those diagnosed with RVOTO, the recipient twins were categorized into two groups based on postnatal outcomes: RVOTO improvement versus persistence. Prenatal ultrasound findings and neonatal outcomes were compared between the groups. To identify the predisposing factors for RVOTO, the entire recipient population was divided into RVOTO and non-RVOTO groups, followed by univariate and multivariable logistic regression analyses.
resultsAmong the 284 TTTS cases, 24 recipient twins (8.5%) were diagnosed with RVOTO. RVOTO improved following FLC in 7 cases (29.2%). In the remaining 17 cases with persistent RVOTO, six were stillbirths. In the 11 survivors, five had mild RVOTO and required no intervention, while six underwent intervention (four with balloon valvuloplasty and two with surgical correction). Multivariate analysis identified the initial Quintero stage (odds ratio [OR] 2.64), pulsatile umbilical vein (OR 3.44), and tricuspid regurgitation (OR 30.66) as significant independent risk factors for RVOTO.
conclusionsRVOTO is a relatively common cardiac complication in advanced TTTS. Timely FLC may lead to postnatal improvement. Serial ultrasound assessment is essential for early detection, risk stratification, and individualized counseling.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.