ArticleBMC pregnancy and childbirth2025
Autologous platelet-rich plasma ovarian injection was associated with increased oocyte acquisition in patients with poor ovarian response: a retrospective propensity-matched study.
Article in BMC pregnancy and childbirth, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWomen with poor ovarian response (POR) tended to have lower success rates for IVF/ICSI due to fewer oocytes retrieved. Autologous platelet-rich plasma (PRP) has been proposed to improve ovarian response.
methodThis study aimed to evaluate the impact of autologous PRP ovarian injections on oocyte retrieval numbers and other reproductive outcomes in IVF/ICSI cycles among infertile women with POR, as defined by the Bologna criteria. Conducted at the Reproductive Center of the Sixth Affiliated Hospital of Sun Yat-sen University, this retrospective analysis involved a total of 1,833 oocyte retrieval cycles. Among these, 91 cycles involved patients who received autologous PRP injections, while 261 cycles were included in the control group after applying propensity score matching.
resultsThe PRP group showed a significant increase in the number of follicles ≥ 14 mm(2.96 ± 1.79 versus 2.26 ± 1.44, P < 0.001), retrieved oocytes(2.86 ± 1.88 versus 2.07 ± 1.78, P < 0.001), and normally fertilized zygotes(1.73 ± 1.42 versus 1.37 ± 1.44, P = 0.044) compared to the control group. Although the number of transferable embryos(1.34 ± 1.21 versus 1.07 ± 1.26, P = 0.079) and high-quality embryos(1.09 ± 1.16 versus 0.83 ± 1.13, P = 0.066) was higher in the PRP group, these differences were not statistically significant. Liner regression identified PRP injection(regression coefficient[B] 0.701, 95% confidence interval [CI] of B 0.324-1.079, P < 0.001), AMH levels(B 1.825, 95% CI of B 0.949-2.701, P < 0.001), and total gonadotropin dose( B < 0.001, 95% CI of B < 0.001-0.001, P = 0.004) as independent predictors for oocyte retrieval.
conclusionAutologous PRP ovarian injection was associated with an increased number of oocytes retrieved in patients with poor response; however, there was no significant improvement in embryo quality. Further randomized controlled trials are warranted to confirm these findings.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.