ArticleBMC microbiology2025
Streptomyces zaomycetitus strain GH90: a source of violet pigment with metabolic profiling and potential application in textile: in vitro supported by in silico studies and molecular docking.
Article in BMC microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Dyes are used daily in the culinary, textile, paper, leather, and agricultural sectors. Synthetic colors pollute the environment and have harmful effects. Microorganism-produced pigments are more cost-effective and environmentally benign than animal, plant, and synthetic pigments. The present study focuses on isolating a pigment-producing actinomycete, a novel violet pigment produced by a local isolate strain identified as S. zaomycetitus GH90, using 16 S rRNA from Egyptian soil. Optimizing violet pigment yield necessitated the precise adjustment of various growth parameters. Streptomyces zaomyceticus GH90 achieved optimal production under specific conditions. pH 8.0, agitation at 180 rpm, temperature at 37 °C, 1.5% starch concentration, ammonium sulfate, dipotassium hydrogen phosphate, 2% inoculum, 20% medium volume, and a 10-day incubation period. Ethanol served as the solvent for pigment extraction. Thermal analysis indicated no degradation at 40 °C. At 50 °C, retention was 98.7% and remained stable at 97.5% when subjected to temperatures between 60 and 80 °C for 1 h. Retention remained above 91% at temperatures of 90 and 100 °C, indicating significant heat stability. The pigment preserved its color integrity in an aqueous solution at pH 8.0. The UV-Vis spectra exhibited a maximum wavelength (λmax) at 580 nm. LC-MS analysis revealed the presence of indole, scopoletin, myricetin, and phosphorylated compounds, which are likely contributors to color and bioactivity. The pigment exhibited superior textile dyeing characteristics, including vivid coloration, high durability, and significant antibacterial activity, establishing it as a versatile and effective dye for antimicrobial textiles. Moreover, the most prevalent molecule, has high permeability, moderate solubility, and selective enzyme interactions, making it a suitable therapeutic candidate. Molecular docking shows significant OMPA and OprD binding affinities, supported by hydrophobic, π-π stacking, and hydrogen bond interactions. The obtained results clearly show how important Streptomyces is as a source of bioactive metabolites with potential applications.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.