Evidence map›Paper›PMID 41044474›Full record

ArticleBMC pediatrics2025

Validity of mid-upper arm circumference in assessing thinness among older children aged 5-9 years: a cross-sectional study.

Terry Namirembe, Ezekiel Mupere, Teddy Namubiru, Peter James Elyanu, Nicolette Nabukeera-Barungi

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Article in BMC pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

5 authors.

Terry NamirembeDepartment of Paediatrics and Child Health, Makerere University College of Health Sciences, P.O. Box 7072, Kampala, Uganda.
Ezekiel MupereDepartment of Paediatrics and Child Health, Makerere University College of Health Sciences, P.O. Box 7072, Kampala, Uganda.
Teddy NamubiruDepartment of Paediatrics and Child Health, Makerere University College of Health Sciences, P.O. Box 7072, Kampala, Uganda.
Peter James ElyanuBaylor College of Medicine Foundation-Uganda, Kampala, Uganda.
Nicolette Nabukeera-BarungiDepartment of Paediatrics and Child Health, Makerere University College of Health Sciences, P.O. Box 7072, Kampala, Uganda. nicolettebarungi@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWith the high burden of malnutrition, accurate yet convenient anthropometric measurements are vital. Although body mass index (BMI) for age and sex z score (BAZ) is the recommended assessment method for children aged 5–9 years, it is quite cumbersome. Uganda adopted use of the convenient mid-upper arm circumference (MUAC) for these children. However, the basis for MUAC use in this age-group is weak, requiring more evidence generation. We therefore determined validity of MUAC in assessing thinness among children aged 5–9 years.

methodsThis was a cross-sectional study. Demographic and anthropometric data was taken from children aged 5–9 years who attended 3 health facilities in Kampala district. MUAC was measured using colour-coded MUAC tapes for children aged 5–9 years and compared with the BAZ. We used a MUAC cut-off of 145 mm for wasting and below 140 mm for severe wasting as per the national guidelines. The sensitivity, specificity, negative and positive predictive values of MUAC were determined using BAZ as the gold standard. Receiver Operating Characteristic curves were plotted to determine the validity of MUAC.

resultsOf the 767 children, 51.5% were female and the mean age was 7.2 +/-1.6 years. According to MUAC, 1% had severe acute malnutrition (SAM), 2.7% moderate acute malnutrition (MAM) and 96.2% had no acute malnutrition. The sensitivity and specificity of MUAC in assessment of acute malnutrition (SAM and MAM) were 22.7%, 95% CI (11.5–37.8) and 97.3%, 95% CI (95.9–98.4) respectively. The positive and negative predictive values were 34.5%, 95% CI (17.9–54.3) and 95.4%, 95% CI (93.6–96.8) respectively. The area under the ROC curve was 0.30, 95%CI (0.206–0.394), indicating MUAC was a poor assessment tool for thinness, even after stratifying for age and Human Immune-deficiency Virus status.

conclusionDespite MUAC being convenient, it showed a low diagnostic performance in assessing thinness among children 5–9 years. This reiterates the need for more research on the correct MUAC cut-offs for this age-group.

Indexed as

AnthropometryArmThinnessBody Mass IndexChildChild, PreschoolCross-Sectional StudiesFemaleHumansMalePredictive Value of TestsReproducibility of ResultsROC CurveSensitivity and SpecificityUgandaBody mass indexMid-upper arm circumferenceOlder childrenThinnessValidity

Identifiers

PMID41044474
PMCPMC12495605

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