Evidence map›Paper›PMID 41044445›Full record

ArticleJournal of human hypertension2025

Comparisons of renin-angiotensin-aldosterone levels measured by chemical luminescence immunoassay and liquid chromatography-tandem mass spectrometry in hypertensive patients under different pathophysiological conditions.

Ting-Ting Xu, Yi-Gui Tang, En-Jun Xu, Xuan-Xuan Wang, Yu-Ping Yang, Zeng Guo

Abstract readClinical StudyComparative Study
In one paragraph

Article in Journal of human hypertension, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ting-Ting XuDepartment of Cardiology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.
Yi-Gui TangDepartment of Laboratory Medicine, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.
En-Jun XuDepartment of Laboratory Medicine, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.
Xuan-Xuan WangDepartment of Laboratory Medicine, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.
Yu-Ping YangDepartment of Laboratory Medicine, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.
Zeng GuoDepartment of Cardiology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China. guozeng1987@126.com.ORCID http://orcid.org/0000-0003-2281-6855

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to compare measurements of the renin-angiotensin-aldosterone system (RAAS) components by liquid chromatography-tandem mass spectrometry (LC-MS/MS) and chemiluminescent immunoassay (CLIA) in hypertensive patients with different gender, position and renal function. EDTA plasma from 100 hypertensive patients who completed postural test were included. Aldosterone (PAC), renin (PRC, using Autobio CLIA microparticles kit; DRC, using LIAISON Direct Renin CLIA kit), angiotensin I and II (AngI and AngII), 18-hydroxycorticosterone (18-OHB) and 18-hydroxycortisol (18-OHF) were measured. Median PAC

Indexed as

AldosteroneHypertensionLuminescent MeasurementsRenin-Angiotensin SystemTandem Mass SpectrometryAdultAgedBiomarkersChromatography, LiquidFemaleHumansImmunoassayMaleMiddle AgedReninAldosteroneBiomarkersRenin

Identifiers

PMID41044445
PMCPMC12592205

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.