Evidence map›Paper›PMID 41044380›Full record

Trial reportEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2025

Evaluation of post-laryngectomy dysphagia rehabilitation using High-Resolution impedance manometry: an exploratory study.

Marise Neijman, Maarten J A van Alphen, Rob J J H van Son, Martijn M Stuiver, Frans J M Hilgers, Michiel W M van den Brekel, Lisette van der Molen

Abstract readClinical Trial, Phase II
PubMed Full text at PMC Publisher
In one paragraph

Trial report in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

7 authors.

Marise NeijmanDepartment of Head and Neck Oncology and Surgery, the Netherlands Cancer Institute, Plesmanlaan 121, Amsterdam, 1066 CX, the Netherlands. m.neijman@nki.nl.ORCID http://orcid.org/0009-0006-1780-3055
Maarten J A van AlphenDepartment of Head and Neck Oncology and Surgery, the Netherlands Cancer Institute, Plesmanlaan 121, Amsterdam, 1066 CX, the Netherlands.
Rob J J H van SonDepartment of Head and Neck Oncology and Surgery, the Netherlands Cancer Institute, Plesmanlaan 121, Amsterdam, 1066 CX, the Netherlands.
Martijn M StuiverDepartment of Head and Neck Oncology and Surgery, the Netherlands Cancer Institute, Plesmanlaan 121, Amsterdam, 1066 CX, the Netherlands.
Frans J M HilgersDepartment of Head and Neck Oncology and Surgery, the Netherlands Cancer Institute, Plesmanlaan 121, Amsterdam, 1066 CX, the Netherlands.
Michiel W M van den BrekelDepartment of Head and Neck Oncology and Surgery, the Netherlands Cancer Institute, Plesmanlaan 121, Amsterdam, 1066 CX, the Netherlands.
Lisette van der MolenDepartment of Head and Neck Oncology and Surgery, the Netherlands Cancer Institute, Plesmanlaan 121, Amsterdam, 1066 CX, the Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimThis exploratory study analyzes High-Resolution Impedance Manometry (HRIM) data obtained during a phase II rehabilitation trial in laryngectomees at baseline (T0), after six-weeks of resistance-based training (T1), and after eight weeks of rest (T2), exploring its potential value in alaryngeal dysphagia research and clinical practice.

methodsPharyngeal HRIM was combined with videofluoroscopy to evaluate swallowing biomechanics in 17 laryngectomy patients. Parameters included Pharyngeal (Velo-, Meso-, and Hypopharyngeal) Contractile Integrals, Intra-Bolus Pressure, UES Relaxation Time, Maximum Admittance, and Integrated Relaxation Pressure.

resultsNo significant differences were found in the Pharyngeal Contractile Integrals, Intra-Bolus Pressure, Relaxation Time, Maximum Admittance, or Integrated Relaxation Pressure. However, pharyngeal pressures and Maximum Admittance slightly decreased from T0 to T1, and increased at T2 for all consistencies (thin, extremely thick, solid).

conclusionAlaryngeal resistance-based swallowing exercises lead to small, non-significant differences in pharyngeal pressures. HRIM provides valuable insights, but its application for this population remains uncertain.

Indexed as

Deglutition DisordersLaryngectomyManometryResistance TrainingAgedDeglutitionElectric ImpedanceFemaleFluoroscopyHumansMaleMiddle AgedPharynxHigh Resolution (Impedance) manometryPharyngeal pressureSwallowing exercise aidSwallowing rehabilitationTotal laryngectomy

Identifiers

PMID41044380
PMCPMC12605583

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.