Evidence map›Paper›PMID 41044300›Full record

ArticleThe international journal of cardiovascular imaging2025

Predict value of ratio of hibernating myocardium in TPD on reverse remodeling and MACEs in HFrEF patients post-revascularization.

Yao Lu, Yanlin Wang, Zihan Liu, Jingjing Meng, Mingkai Yun, Ran Dong, Xiaoli Zhang

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Article in The international journal of cardiovascular imaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Yao Lu *Department of Nuclear Medicine, Laboratory for Molecular Imaging, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Yanlin Wang *Department of Nuclear Medicine, Laboratory for Molecular Imaging, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Zihan LiuDepartment of Nuclear Medicine, Laboratory for Molecular Imaging, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Jingjing MengDepartment of Nuclear Medicine, Laboratory for Molecular Imaging, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Mingkai YunDepartment of Nuclear Medicine, Laboratory for Molecular Imaging, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Ran DongDepartment of Cardiovascular Surgery Center, Beijing Anzhen Hospital, Beijing, China. dongran6618@hotmail.com.
Xiaoli ZhangDepartment of Nuclear Medicine, Laboratory for Molecular Imaging, Beijing Anzhen Hospital, Capital Medical University, Beijing, China. xlzhang68@126.com.

Funding

Beijing Hospitals Authority Clinical Medicine Development of special funding support ZYLX202110Beijing Municipal Natural Science Foundation 7232040National Natural Science Foundation of China 82171994
6 · The paper itself

Abstract

purposeThis study aimed to assess the predictive value of hibernating myocardium (HM) proportion in total perfusion deficit (TPD) for reverse left ventricular (LV) remodeling and its prognostic significance in heart failure with reduced ejection fraction (HFrEF) patients after revascularization.

methodsA retrospective analysis of 201 HFrEF patients (178 males, 60.6 ± 9.3 years) who underwent gated myocardial perfusion imaging,

resultsHM/TPD independently predicted RR (OR = 1.042, 95%CI: 1.019-1.065, P < 0.001). A HM/TPD cutoff of 38.5% demonstrated significant associations with reversed LV remodeling and improved cardiac function post-revascularization, along with a favorable prognosis. The prospective cohort validated these findings. ΔTPD positively correlated with ΔHM (r = 0.825, P < 0.001).

conclusionsHigher HM/TPD proportion in HFrEF patients was associated with an increased likelihood of RR, improved cardiac function, and favorable outcomes post-revascularization. These findings warrant further prospective investigations.

Indexed as

Coronary CirculationHeart FailureMyocardial Perfusion ImagingMyocardial StunningMyocardiumPositron Emission Tomography Computed TomographyStroke VolumeVentricular Function, LeftVentricular RemodelingAgedEchocardiographyFemaleFluorodeoxyglucose F18HumansMaleMiddle AgedFluorodeoxyglucose F18RadiopharmaceuticalsHeart failureHibernating myocardiumMACEsReverse remodeling

Identifiers

PMID41044300

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.