Evidence map›Paper›PMID 41044175›Full record

ArticleBritish journal of cancer2025

Intake of total, classes, and subclasses of (poly)phenols and risk of lymphoid neoplasms: a prospective analysis in the EPIC cohort.

Enrique Almanza-Aguilera, David Guananga-Álvarez, Yolanda Benavente, Alexandra Nieters, Caroline Besson, Fatemeh Saberi Hosnijeh, Cecilie Kyrø, Nicola P Bondonno, Christina C Dahm, Elisabete Weiderpass and 19 more

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Article in British journal of cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

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No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

29 authors.

Enrique Almanza-Aguilera *Unit of Nutrition and Cancer, Cancer Epidemiology Research Program, IDIBELL, Catalan Institute of Oncology, L'Hospitalet de Llobregat, Spain, Barcelona, Spain.ORCID http://orcid.org/0000-0002-4805-0774
David Guananga-Álvarez *Unit of Infections and Cancer, Cancer Epidemiology Research Programme, IDIBELL, Catalan Institute of Oncology, L'Hospitalet de Llobregat, Spain.
Yolanda BenaventeUnit of Infections and Cancer, Cancer Epidemiology Research Programme, IDIBELL, Catalan Institute of Oncology, L'Hospitalet de Llobregat, Spain.
Alexandra NietersCenter for Chronic Immunodeficiency (CCI), Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Caroline BessonDepartment of Hematology and Oncology, Hospital of Versailles, Le Chesnay, France.ORCID http://orcid.org/0000-0003-4364-7173
Fatemeh Saberi HosnijehInstitute for Risk Assessment Sciences, Division of Environmental Epidemiology, Utrecht University, Utrecht, The Netherlands.
Cecilie KyrøThe Danish Cancer Institute, Copenhagen, Denmark.
Nicola P BondonnoThe Danish Cancer Institute, Copenhagen, Denmark.ORCID http://orcid.org/0000-0001-5905-444X
Christina C DahmDepartment of Public Health, Aarhus University, Aarhus, Denmark.ORCID http://orcid.org/0000-0003-0481-2893
Elisabete WeiderpassInternational Agency for Research on Cancer (IARC/WHO), Lyon, France.ORCID http://orcid.org/0000-0003-2237-0128
Therese TruongUniversité Paris-Saclay, UVSQ, Inserm, Gustave Roussy, Team "Exposome, Heredity, Cancer and Health", CESP, Villejuif, France.ORCID http://orcid.org/0000-0002-2943-6786
Mariem Louati-HajjiUniversité Paris-Saclay, UVSQ, Inserm, Gustave Roussy, Team "Exposome, Heredity, Cancer and Health", CESP, Villejuif, France.
Xuan RenUniversité Paris-Saclay, UVSQ, Inserm, Gustave Roussy, Team "Exposome, Heredity, Cancer and Health", CESP, Villejuif, France.
Verena KatzkeDivision of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Matthias B SchulzeDepartment of Molecular Epidemiology, German Institute of Human Nutrition Potsdam-Rehbruecke, Nuthetal, Germany.
Fabrizio PasanisiInternal Medicine and Clinical Nutrition, Department of Clinical Medicine and Surgery, Federico II University Hospital, Naples, Italy.
Claudia VenerEpidemiology and Prevention Unit, Department of Epidemiology and Data Science, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Milan, Italy.
Giovanna MasalaInstitute for Cancer Research, Prevention and Clinical Network (ISPRO), Florence, Italy.
Maria Teresa GiraudoCentre for Biostatistics, Epidemiology and Public Health (C-BEPH), Department of Clinical and Biological Sciences, University of Turin, Orbassano, Italy.
Rosario TuminoHyblean Association for Epidemiological Research, AIRE-ONLUS Ragusa, Ragusa, Italy.ORCID http://orcid.org/0000-0003-2666-414X
Amaia AizpuruaBioGipuzkoa (BioDonostia) Health Research Institute, Epidemiology of Chronic and Communicable Diseases Group, San Sebastián, Spain.
Maria-Jose SánchezCentro de Investigación Biomédica en Red de Epidemiología y Salud Pública (CIBERESP), Madrid, Spain.
José María HuertaCentro de Investigación Biomédica en Red de Epidemiología y Salud Pública (CIBERESP), Madrid, Spain.
Marcela GuevaraCentro de Investigación Biomédica en Red de Epidemiología y Salud Pública (CIBERESP), Madrid, Spain.
Cristina LasherasFunctional Biology Department, University of Oviedo, Oviedo, Spain.
Paolo VineisMRC Centre for Environment and Health, Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK.
Roel VermeulenInstitute for Risk Assessment Sciences, Division of Environmental Epidemiology, Utrecht University, Utrecht, The Netherlands.ORCID http://orcid.org/0000-0003-4082-8163
Raul Zamora-RosUnit of Nutrition and Cancer, Cancer Epidemiology Research Program, IDIBELL, Catalan Institute of Oncology, L'Hospitalet de Llobregat, Spain, Barcelona, Spain.
Delphine CasabonneUnit of Infections and Cancer, Cancer Epidemiology Research Programme, IDIBELL, Catalan Institute of Oncology, L'Hospitalet de Llobregat, Spain. dcasabonne_ext@iconcologia.net.ORCID http://orcid.org/0000-0002-7874-3707

Funding

World Health Organization 001
6 · The paper itself

Abstract

backgroundExisting epidemiological evidence regarding the potential role of (poly)phenol intake in lymphoma development is limited.

methodsWe investigated the associations between the intake of total and individual classes and subclasses of (poly)phenols and the risk of lymphoma, including main frequent subtypes in the EPIC cohort using multivariable-adjusted Cox proportional hazards models.

resultsDuring a mean 14-year follow-up (time frame: from 1990-1994 to 2008-2013), 2394 incident lymphoma cases were diagnosed from a total of 367,463 individuals. No significant associations were observed between total intakes of (poly)phenols, flavonoids, and phenolic acids and overall lymphoma risk. Total (poly)phenols, phenolic acid and hydroxycinnamic acid intakes were positively associated with Hodgkin lymphoma (HL) risk [HR

conclusionsOur findings suggest that isoflavone intakes may reduce the risk of overall lymphoma and specific lymphoma subtypes, while phenolic acids, particularly hydroxycinnamic acids might increase the risk of HL.

Indexed as

LymphomaPolyphenolsAdultAgedDietFemaleHodgkin DiseaseHumansMaleMiddle AgedProportional Hazards ModelsProspective StudiesRisk FactorsPolyphenols

Identifiers

PMID41044175
PMCPMC12689600

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.