Evidence map›Paper›PMID 41044021›Full record

ArticleGait & posture2026

Whole-body angular momentum is influenced by bone-anchored limb use and amputation level during walking.

Brecca M M Gaffney, Peter B Thomsen-Freitas, Grace M Georgiou, Danielle H Melton, Cory L Christiansen, Jason W Stoneback

Abstract read
In one paragraph

Article in Gait & posture, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Brecca M M GaffneyDepartment of Mechanical Engineering, University of Colorado Denver, Denver, CO, United States; Department of Bioengineering, University of Colorado Anschutz Medical Campus, Aurora, CO, United States; Eastern Colorado VA Geriatric Research Education and Clinical Center, Aurora, CO, United States; Univerisity of Colorado Bone-Anchored Limb Research Group, Aurora, CO, United States. Electronic address: brecca.gaffney@ucdenver.edu.
Peter B Thomsen-FreitasEastern Colorado VA Geriatric Research Education and Clinical Center, Aurora, CO, United States; Department of Physical Medicine and Rehabilitation, University of Colorado Anschutz Medical Campus, Aurora, CO, United States; Univerisity of Colorado Bone-Anchored Limb Research Group, Aurora, CO, United States.
Grace M GeorgiouDepartment of Bioengineering, University of Colorado Anschutz Medical Campus, Aurora, CO, United States.
Danielle H MeltonDepartment of Physical Medicine and Rehabilitation, University of Colorado Anschutz Medical Campus, Aurora, CO, United States; Univerisity of Colorado Bone-Anchored Limb Research Group, Aurora, CO, United States.
Cory L ChristiansenEastern Colorado VA Geriatric Research Education and Clinical Center, Aurora, CO, United States; Department of Physical Medicine and Rehabilitation, University of Colorado Anschutz Medical Campus, Aurora, CO, United States; Univerisity of Colorado Bone-Anchored Limb Research Group, Aurora, CO, United States.
Jason W StonebackDepartment of Orthopedics, University of Colorado Anschutz Medical Campus, Aurora, CO, United States; Univerisity of Colorado Bone-Anchored Limb Research Group, Aurora, CO, United States.

Funding

NIH Prior Approval Process ProfessionalUL1TR002535 · NCATS · UNIVERSITY OF COLORADO DENVER · PI SOKOL, RONALD J. · 2018 to 2022
$51.1M
Colorado Clinical and Translational Sciences Institute (CCTSI)UM1TR004399 · NCATS · UNIVERSITY OF COLORADO DENVER · PI JANINE A HIGGINS, RONALD J. SOKOL · 2023 to 2026
$30.7M
Colorado Clinical and Translational Science Institute (UL1)UL1TR000154 · NCATS · UNIVERSITY OF COLORADO DENVER · PI SOKOL, RONALD J. · 2012 to 2013
$20.4M
Interdisciplinary Training in Musculoskeletal ResearchT32AR080630 · NIAMS · UNIVERSITY OF COLORADO DENVER · PI Karin A Payne, MICHAEL J ZUSCIK · 2022 to 2026
$1.7M
Effect of Osseointegrated Prostheses on the Pathogenesis of Hip Osteoarthritis in Patients with Lower Limb LossK01AR080776 · NIAMS · UNIVERSITY OF COLORADO DENVER · PI Brecca Gaffney · 2023 to 2026
$522k
NCATS NIH HHS UL1 TR000154NCATS NIH HHS UL1 TR002535NCATS NIH HHS UM1 TR004399NIAMS NIH HHS K01 AR080776NIAMS NIH HHS T32 AR080630
6 · The paper itself

Abstract

backgroundBone-anchored limbs (BALs) improve mobility, physical activity, multi-joint biomechanics, and static balance measures compared to when using a socket prosthesis. However, evidence surrounding how BAL use influences dynamic balance, and whether this is dependent on amputation level, remains unknown. RESEARCH QUESTIONS: Does BAL use change dynamic balance as compared to a socket prosthesis? Do changes in dynamic balance with BAL use differ by amputation level?

methodsThirty-two participants with prior unilateral amputation (19 transfemoral, 13 transtibial) who underwent BAL implantation were retrospectively enrolled. Whole-body motion capture data during overground level walking was collected before (using socket prosthesis) and 12-months after BAL implantation. The range of whole-body angular momentum (WBAM) and peak external demand moment were compared across timepoints and groups using a two-way mixed model ANOVA.

resultsFrontal and transverse plane WBAM were reduced in individuals with transfemoral amputation when using a BAL as compared to a socket prosthesis (p < 0.001 and p < 0.001, respectively). Furthermore, when using a BAL or socket prosthesis, frontal plane WBAM was larger in individuals with transfemoral amputation compared to transtibial amputation (p = 0.028 and p = 0.018), which coincided with a larger peak external demand moment (p = 0.027 and p = 0.007). SIGNIFICANCE: Smaller ranges of WBAM and a smaller external demand moment during walking indicate improved dynamic stability when using a BAL compared to socket-type prosthesis, and thus likely suggest a reduced fall risk. As walking is most unstable in the mediolateral direction, greater ranges of frontal plane WBAM (worsened regulation) in individuals with transfemoral amputation compared to transtibial amputation may indicate more compromised balance control and greater fall risk.

Indexed as

Amputation, SurgicalArtificial LimbsBone-Anchored ProsthesisPostural BalanceWalkingAdultAgedAmputeesBiomechanical PhenomenaFemaleHumansMaleMiddle AgedProsthesis DesignRetrospective StudiesTibiaDynamic balanceOsseointegrated prosthesisOsseointegrationTransfemoral amputationTranstibial amputationWhole-body angular momentum

Identifiers

PMID41044021
PMCPMC12685126

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.