Evidence map›Paper›PMID 41043940›Full record

ReviewJACC. Advances2025

Navigating Hypoxemic Respiratory Failure in Critically Ill Cardiac Patients.

Lee H Sterling, Shannon M Fernando, Patrick R Lawler, Susanna Price, Eddy Fan, Ewan Goligher, Rebecca Mathew

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in JACC. Advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lee H SterlingCAPITAL Research Group, Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada; Division of Critical Care Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
Shannon M FernandoCAPITAL Research Group, Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada; Department of Critical Care Medicine, Queen's University, Kingston, Ontario, Canada; Department of Critical Care, Lakeridge Health, Oshawa, Ontario, Canada; Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.
Patrick R LawlerInterdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, Ontario, Canada; Division of Cardiology, McGill University Health Centre, Montreal, Quebec, Canada.
Susanna PriceDepartments of Cardiology & Critical Care, Royal Brompton Hospital, National Heart & Lung Institute, Imperial College, London, United Kingdom.
Eddy FanInterdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, Ontario, Canada; Toronto General Hospital Research Institute, University Health Network, Toronto, Ontario, Canada.
Ewan GoligherInterdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, Ontario, Canada; Toronto General Hospital Research Institute, University Health Network, Toronto, Ontario, Canada.
Rebecca MathewCAPITAL Research Group, Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada; Department of Critical Care, The Ottawa Hospital, Ottawa, Ontario, Canada. Electronic address: rmathew@ottawaheart.ca.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute respiratory failure is a common reason for admission to cardiac intensive care units and the prevalence of respiratory failure in this cohort is increasing over time. Hypoxemia can occur due to a variety of mechanisms; the most common cause in the cardiac intensive care units remains cardiogenic pulmonary edema, but other etiologies, such as pneumonia and acute respiratory distress syndrome, are also common. This article provides an update on mechanisms of hypoxemia among patients with cardiac critical illness, heart lung interactions during spontaneous and positive pressure ventilation, optimization of sedation and ventilation for cardiac patients including novel ventilation strategies, and management of refractory hypoxemia among patients with cardiac critical illness.

Indexed as

cardiac intensive careheart-lung interactionsinvasive mechanical ventilation

Identifiers

PMID41043940
PMCPMC12541218

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.