Evidence map›Paper›PMID 41043422›Full record

ArticleNeuron2025

Hippocampal ripple diversity organizes neuronal reactivation dynamics in the offline brain.

Manfredi Castelli, Vítor Lopes-Dos-Santos, Giuseppe P Gava, Renaud Lambiotte, David Dupret

Abstract read
In one paragraph

Article in Neuron, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
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  7. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Manfredi CastelliMedical Research Council Brain Network Dynamics Unit, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK. Electronic address: manfredi.castelli@ndcn.ox.ac.uk.
Vítor Lopes-Dos-SantosMedical Research Council Brain Network Dynamics Unit, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK. Electronic address: vitor.lopesdossantos@ndcn.ox.ac.uk.
Giuseppe P GavaMedical Research Council Brain Network Dynamics Unit, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK.
Renaud LambiotteMathematical Institute, University of Oxford, Oxford, UK.
David DupretMedical Research Council Brain Network Dynamics Unit, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK. Electronic address: david.dupret@bndu.ox.ac.uk.

Funding

Medical Research Council MC_UU_00003/4Medical Research Council MC_UU_12024/3Medical Research Council MR/W004860/1
6 · The paper itself

Abstract

Hippocampal ripples are highly synchronized neuronal population patterns reactivating past waking experiences in the offline brain. Whether the level, structure, and content of ripple-nested activity are consistent across consecutive events or are tuned in each event remains unclear. By profiling individual ripples using laminar currents in the mouse hippocampus during sleep/rest, we identified ripples in stratum pyramidale that feature current sinks in stratum radiatum (Rad

Indexed as

CA1 Region, HippocampalHippocampusNeuronsSleepWakefulnessAnimalsMaleMiceMice, Inbred C57BLCA1hippocampusnetwork patternsneuronal populationsoffline computationsprincipal cellsreactivationripplessleep

Identifiers

PMID41043422
PMCPMC7618225

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.