Evidence map›Paper›PMID 41042872›Full record

ArticleScience advances2025

Single-cell atlas of cervical organoids uncovers epithelial immune heterogeneity and intercellular cross-talk during Chlamydia infection.

Pon Ganish Prakash, Naveen Kumar, Stefanie Koster, Christian Wentland, Jayabhuvaneshwari Dhanraj, Rajendra Kumar Gurumuthy, Cindrilla Chumduri

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Science advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. ECHOS enables spatial epigenome profiling at subcellular resolution.bioRxiv : the preprint server for biology · 2026
    Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Pon Ganish PrakashDepartment of Microbiology, University of Würzburg, Würzburg, Germany.ORCID 0000-0003-1754-6555
Naveen KumarDepartment of Microbiology, University of Würzburg, Würzburg, Germany.ORCID 0000-0002-2026-0446
Stefanie KosterDepartment of Molecular Biology, Max Planck Institute for Infection Biology, Berlin, Germany.ORCID 0000-0001-8449-9985
Christian WentlandDepartment of Microbiology, University of Würzburg, Würzburg, Germany.ORCID 0009-0007-7405-756X
Jayabhuvaneshwari DhanrajDepartment of Microbiology, University of Würzburg, Würzburg, Germany.
Rajendra Kumar GurumuthyDepartment of Microbiology, University of Würzburg, Würzburg, Germany.ORCID 0000-0001-6479-8080
Cindrilla ChumduriDepartment of Microbiology, University of Würzburg, Würzburg, Germany.ORCID 0000-0003-3290-5966

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The uterine cervix is a critical mucosal interface that balances immune defense and reproductive function, yet how its distinct epithelial compartments coordinate responses to infection remains unclear. Here, we integrate patient-derived three-dimensional cervical organoids, single-cell transcriptomics, and native tissue analysis to construct a high-resolution atlas of epithelial cell diversity and immune dynamics during

Indexed as

Cell CommunicationCervix UteriChlamydia InfectionsChlamydia trachomatisEpithelial CellsOrganoidsSingle-Cell AnalysisFemaleHost-Pathogen InteractionsHumansTranscriptome

Identifiers

PMID41042872
PMCPMC12494012

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.