Evidence map›Paper›PMID 41042749›Full record

ArticlePloS one2025

Integrating feature importance techniques and causal inference to enhance early detection of heart disease.

Atousa Arzanipour

Abstract read
In one paragraph

Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Atousa ArzanipourDepartment of Industrial and Manufacturing Systems Engineering, Iowa State University, Ames, Iowa, United States of America.ORCID https://orcid.org/0000-0001-6854-6972

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Heart disease remains a leading cause of mortality worldwide, necessitating robust methods for its early detection and intervention. This study employs a comprehensive approach to identify and analyze critical features contributing to heart disease. Using a dataset of 270 patients, three well-known feature importance techniques-Boruta, Information Gain, and Lasso Regression-are applied to determine the top five features for heart disease detection. Following the identification of these key features, the g-computation method, a causal inference technique, is utilized to explore the causal relationships between these features and the presence of heart disease. The innovation of this research lies in providing valuable insights not only into the features that are highly correlated with chronic heart disease but also into those that have a direct causal impact on patient classification, using a well-known causal inference technique, g-estimation. This integrated approach enhances the understanding of heart disease etiology and can inform more effective diagnostic and therapeutic strategies.

Indexed as

Heart DiseasesAlgorithmsEarly DiagnosisFemaleHumansMaleMiddle Aged

Identifiers

PMID41042749
PMCPMC12494272

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.