Evidence map›Paper›PMID 41042679›Full record

ArticleVirulence2025

Stem cell-derived brain-like endothelial cells to interrogate

Henry D Mauser, Taryn E Keyzer, Jessica M Surma, Natalie G Alexander, William D Cutts, Sarah F Hathcock, Kimberly H Lackey, Daryl W Lam, Justin A Thornton, Nadine Vollmuth and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Virulence, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Henry D MauserDepartment of Biological Sciences, University of Alabama, Tuscaloosa AL, USA.ORCID 0009-0006-0080-9725
Taryn E KeyzerDepartment of Biological Sciences, University of Alabama, Tuscaloosa AL, USA.ORCID 0009-0008-8185-4636
Jessica M SurmaDepartment of Biological Sciences, Mississippi State University, Starkville MS, USA.
Natalie G AlexanderDepartment of Biological Sciences, University of Alabama, Tuscaloosa AL, USA.ORCID 0000-0001-8847-4347
William D CuttsDepartment of Biological Sciences, University of Alabama, Tuscaloosa AL, USA.ORCID 0000-0002-7881-2127
Sarah F HathcockDepartment of Biological Sciences, University of Alabama, Tuscaloosa AL, USA.ORCID 0009-0002-6699-3263
Kimberly H LackeyDepartment of Biological Sciences, University of Alabama, Tuscaloosa AL, USA.ORCID 0000-0001-6139-0311
Daryl W LamDepartment of Biological Sciences, University of Alabama, Tuscaloosa AL, USA.
Justin A ThorntonDepartment of Biological Sciences, Mississippi State University, Starkville MS, USA.
Nadine VollmuthDepartment of Biological Sciences, University of Alabama, Tuscaloosa AL, USA.ORCID 0000-0002-1003-4410
Brandon J KimDepartment of Biological Sciences, University of Alabama, Tuscaloosa AL, USA.

Funding

Rational design of an adhesin-based pneumococcal vaccine targeting colonizationR15AI142537 · NIAID · MISSISSIPPI STATE UNIVERSITY · PI THORNTON, JUSTIN A · 2020 to 2025
$946k
Impairment of the cerebral vasculature during bacterial meningitisR15NS131921 · NINDS · UNIVERSITY OF ALABAMA IN TUSCALOOSA · PI CORRELL, ROBERT NATHAN · 2023 to 2023
$447k
A Group B Streptococcus ordered CRISPR interference library to investigate host-pathogen interactionsR03AI185593 · NIAID · UNIVERSITY OF TEXAS DALLAS · PI KIM, BRANDON JONATHAN · 2024 to 2025
$153k
NIAID NIH HHS R03 AI185593NIAID NIH HHS R15 AI142537NINDS NIH HHS R15 NS131921
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Blood-Brain BarrierBrainEndothelial CellsStreptococcus pneumoniaeAdhesins, BacterialBacterial AdhesionHumansPneumococcal InfectionsTight JunctionsAdhesins, Bacterialblood-brain barrierbrain endothelial cellsiPSC-BECpneumococcal meningitisStreptococcus pneumoniae

Identifiers

PMID41042679
PMCPMC12498544

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.