Evidence map›Paper›PMID 41042455›Full record

ArticleJournal of racial and ethnic health disparities2025

Relations of Social Determinants of Health to Pain and Function in Individuals with Knee Osteoarthritis in a Hispanic-dominant Community.

Kosaku Aoyagi, Michael LaValley, Tuhina Neogi, Robert Edwards, Roxanna Shababi, Elias Rivas, Sudip Bajpeyi, Abhijit Mandal, Eva Moya, Julia Lechuga

Abstract read
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Article in Journal of racial and ethnic health disparities, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Kosaku AoyagiDepartment of Physical Therapy and Movement Sciences, The University of Texas at El Paso, 3333 N Mesa St, Room 115D, El Paso, TX, 79902, USA. kaoyagi@utep.edu.ORCID http://orcid.org/0000-0002-9221-5855
Michael LaValleySchool of Public Health, Boston University, Boston, MA, 02118, USA.
Tuhina NeogiChobanian & Avedisian School of Medicine, Boston University, Boston, MA, USA.
Robert EdwardsBrigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Roxanna ShababiDepartment of Physical Therapy and Movement Sciences, The University of Texas at El Paso, 3333 N Mesa St, Room 115D, El Paso, TX, 79902, USA.
Elias RivasDepartment of Physical Therapy and Movement Sciences, The University of Texas at El Paso, 3333 N Mesa St, Room 115D, El Paso, TX, 79902, USA.
Sudip BajpeyiDepartment of Physical Therapy and Movement Sciences, The University of Texas at El Paso, 3333 N Mesa St, Room 115D, El Paso, TX, 79902, USA.
Abhijit MandalDepartment of Physical Therapy and Movement Sciences, The University of Texas at El Paso, 3333 N Mesa St, Room 115D, El Paso, TX, 79902, USA.
Eva MoyaDepartment of Physical Therapy and Movement Sciences, The University of Texas at El Paso, 3333 N Mesa St, Room 115D, El Paso, TX, 79902, USA.
Julia LechugaDepartment of Physical Therapy and Movement Sciences, The University of Texas at El Paso, 3333 N Mesa St, Room 115D, El Paso, TX, 79902, USA.

Funding

TCCG12MD007592 · NIMHD · UNIVERSITY OF TEXAS EL PASO · PI KIRKEN, ROBERT A. · 2012 to 2018
$19.4M
Research and Evaluation Support Core Unit (RESCU Core)P30AR072571 · NIAMS · BOSTON UNIVERSITY MEDICAL CAMPUS · PI TUHINA NEOGI · 2019 to 2026
$6.9M
Pain in community-based older African American Adults: The Jackson Heart StudyR01AG066914 · NIA · BOSTON UNIVERSITY MEDICAL CAMPUS · PI BENJAMIN, EMELIA J., EDWARDS, ROBERT R · 2020 to 2024
$3.2M
The Role of Urate in Knee Osteoarthritis-Related Inflammation, Pathology and PainK24AR070892 · NIAMS · BOSTON UNIVERSITY MEDICAL CAMPUS · PI TUHINA NEOGI · 2017 to 2026
$1.1M
NIAMS NIH HHS K24 AR070892NIAMS NIH HHS P30 AR072571NIA NIH HHS R01 AG066914NIMHD NIH HHS G12 MD007592
6 · The paper itself

Abstract

backgroundSocial determinants of health have been associated with knee osteoarthritis (OA) symptoms. However, there is a dearth of research on the influence of social determinants of health on knee OA among Hispanics despite Hispanics being disproportionately impacted by racial/ethnic disparities in pain and function. Thus, we sought to investigate the relations of social determinants of health to pain and function in individuals with knee OA in a Hispanic-dominant community.

methodsWe included participants residing in El Paso, Texas, a major Hispanic community in the US. We evaluated relations of income level, education level and perceived discrimination to The Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) knee pain, quantitative sensory testing (QST) measures of pressure pain threshold (PPT), temporal summation (TS) and conditioned pain modulation (CPM), and WOMAC function using linear or logistic regression models adjusting for age, sex and BMI.

resultsFifty-nine participants with knee OA were included (76% Hispanic). Higher income and education levels were associated with less knee pain and better function. Higher income and education levels had non-significant trends toward associations with non-facilitated TS and higher PPT, respectively. In contrast, perceived discrimination was not associated with any of the outcomes.

conclusionsWe found that income and education levels were associated with pain and function and showed non-significant associations with central pain sensitization assessed by PPT and TS. Perceived discrimination was not associated with any outcome. These findings underscore the importance of social determinants of health in precision pain management for Hispanic individuals with knee OA.

Indexed as

Central pain mechanismsFunctionHispanicKnee osteoarthritisPainRacial/ethnic disparities in pain

Identifiers

PMID41042455
PMCPMC13637560

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.