Evidence map›Paper›PMID 41042421›Full record

ReviewDiscover oncology2025

The role of LncRNA SNHG3 in human cancers.

Jinming Tang, Min Su, Yuhang Xiao, Wei Ou, Wenxiang Wang, Ren-Wang Peng, Zhining Wu

Abstract readReview
In one paragraph

Review in Discover oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jinming Tang *Hunan Clinical Medical Research Center of Accurate Diagnosis and Treatment for Esophageal Carcinoma, The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University/Hunan Cancer Hospital, Changsha, 410013, Hunan, China.
Min Su *Hunan Clinical Medical Research Center of Accurate Diagnosis and Treatment for Esophageal Carcinoma, The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University/Hunan Cancer Hospital, Changsha, 410013, Hunan, China.
Yuhang Xiao *Department of Pharmacy, Xiangya Hospital of Xiangya School of Medicine, Central South University, Changsha, 410013, Hunan, China.
Wei OuDepartment of Pharmacy, YUEYANG Central Hospital, Yue Yang, 414003, Hunan, China.
Wenxiang WangHunan Clinical Medical Research Center of Accurate Diagnosis and Treatment for Esophageal Carcinoma, The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University/Hunan Cancer Hospital, Changsha, 410013, Hunan, China. hnchw11@163.com.
Ren-Wang PengDepartment of General Thoracic Surgery, Inselspital, Bern University Hospital, Murtenstrasse 50, 3008 Bern, Switzerland. Renwang.Peng@insel.ch.
Zhining WuHunan Clinical Medical Research Center of Accurate Diagnosis and Treatment for Esophageal Carcinoma, The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University/Hunan Cancer Hospital, Changsha, 410013, Hunan, China. wuzhining@hnca.org.cn.

Funding

Hunan Cancer Hospital Climb Plan 2021NSFC-002National Natural Science Foundation of China 82173012Natural Science Foundation of Hunan Province 2023JJ30952Natural Science Foundation of Hunan Province 2023JJ60332Science and Technology Innovation Program of Hunan Province 2024RC3284Scientific Research Project of Hunan Provincial Health Commission 20256912
6 · The paper itself

Abstract

An essential category of non-protein-coding RNA molecules, known as long noncoding RNAs (lncRNAs), are naturally occurring RNA sequences exceeding 200 nucleotides in length. Accumulating evidence has unveiled the significant involvement of lncRNAs in various cancers, where they are known to be a key factor for tumors' statement changing, e.g., modulating proliferative, apoptotic, migratory and chemotherapy resistance in cells. In addition, lncRNAs are also regarded as potential diagnostic and prognostic tumor biomarkers. Studies have suggested that lncRNAs modulate biological processes by regulating linear RNA transcription and protein production. A recently discovered long non-coding RNA, SNHG3, is identified to have associations with cancer, which displays atypical expression patterns and functions as an oncogene in various cancers. Additionally, SNHG3 has been demonstrated to hold promise as a diagnostic biomarker and a tool for prognostic assessment in cancer patients. This review summarizes current knowledge about SNHG3's expression, functional roles, molecular mechanisms, and implications for diagnosis and prognosis in human cancers.

Indexed as

Human cancerLong noncoding RNAOncogeneSNHG3

Identifiers

PMID41042421
PMCPMC12494508

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.