Evidence map›Paper›PMID 41042418›Full record

ReviewDiscover oncology2025

GlycoRNA, a novel RNA modification.

Binbin Hu, Tianyu Ma, Dongli Zhou, Juan Jiao, Xiangwei Xia

Abstract readReview
In one paragraph

Review in Discover oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Binbin HuCancer Institue, GaoYou People's Hospital, Gaoyou, 225600, People's Republic of China.
Tianyu MaCancer Institue, GaoYou People's Hospital, Gaoyou, 225600, People's Republic of China.
Dongli ZhouCancer Institue, GaoYou People's Hospital, Gaoyou, 225600, People's Republic of China.
Juan JiaoCancer Institue, GaoYou People's Hospital, Gaoyou, 225600, People's Republic of China.
Xiangwei XiaCancer Institue, GaoYou People's Hospital, Gaoyou, 225600, People's Republic of China. xxw475gyry@163.com.

Funding

Medical scientific research project of Gaoyou Health Committee in 2022 gy20221203
6 · The paper itself

Abstract

RNA plays a variety of critical roles in cellular environments, including serving as a structural molecule, messenger molecule, translational carrier, and effector molecule. During the execution of these functions, RNA undergoes diverse post-transcriptional chemical modifications, which are essential for sustaining life processes. Glycosylation, a key biological modification, was traditionally thought to occur only in lipids and proteins. However, recent studies have revealed that it can also take place on RNA, giving rise to what is termed glycosylated RNA (glycoRNA). This article explores the mechanisms underlying the formation and function of glycoRNA, detection methods, extracellular binding proteins, and key enzymatic systems involved. Furthermore, it highlights the potential of glycoRNA research to provide new insights for precision cancer therapy.

Indexed as

BiomarkerCancerGlycoRNARNA glycosylation

Identifiers

PMID41042418
PMCPMC12494505

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.