ArticleMolecular biology reports2025
Celery root-plant derived vesicles: comprehensive isolation, characterization and proteomic analysis.
Article in Molecular biology reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Proteomic mapping of Rosa damascena nanovesicles reveals plastid mitochondrial metabolic convergence and antimicrobial peptides.Plant signaling & behavior · 2026Article
- Plant-Derived Nanovesicles: A Comprehensive Review from Isolation to Clinical Translation-Unlocking Natural Nanocarriers for Biomedical Applications.Biomolecules · 2026Review
- Extracellular vesicles-mediated communication between glioblastoma and astrocytes promotes pro-tumorigenic activation.Medical oncology (Northwood, London, England) · 2026Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
backgroundDespite its potent antioxidant and anti-inflammatory capacities, celery (Apium graveolens) root has not been studied as much as its leaf portion. Plant-derived vesicles (PDVs) are emerging biotechnological tools as biocompatible nanocarriers; however, detailed characterization of celery root-derived PDVs (CR-PDVs) is lacking in the literature. This study aimed to comprehensively characterize the physical and proteomic properties of CR-PDVs for the first time, demonstrating their innovative potential in disease modeling and therapeutic applications. METHODS AND
resultsCR-PDVs were purified using the Aqueous Two-Phase System (ATPS) protocol. Morphology, size distribution, and particle density were measured by Nanoparticle Tracking Analysis (NTA). The vesicle proteome was characterized by LC-MS/MS, and proteins were functionally classified using Gene Ontology and KEGG enrichment analyses. CR-PDVs were homogeneous spherical structures with a modal diameter of 147.6 ± 3 nm and yielded 1.15 × 10
conclusionsCR-PDVs, with their high structural integrity and biologically rich cargo, can be evaluated as innovative drug carriers or biomarker platforms in cancer, neurodegenerative, and autoimmune disease models. This study provides the first comprehensive dataset on CR-PDVs, providing a solid foundation for translational research.
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Registered trials
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