ArticleAnnals of hematology2025
Epidemiological study of thalassemia in the Buyi population of Qiannan Prefecture, Guizhou Province, China based on third-generation sequencing.
Article in Annals of hematology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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2 citing papers in PubMed.
- Third-generation sequencing technology in the prevention and control of thalassemia: Applications and advances.The Journal of international medical research · 2026Review
- Cord blood-based neonatal genetic screening for thalassemia in Guiyang, China (2015): a cross-sectional study.Frontiers in genetics · 2026Article
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11 authors.
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Abstract
This genetic epidemiological study aimed to investigate the prevalence of various types of thalassemia among the Buyi population in Qiannan Prefecture, Guizhou Province, China. A total of 1,003 Buyi individuals from five regions in Qiannan Prefecture were enrolled for this study. Peripheral blood samples were collected for routine blood testing and hemoglobin electrophoresis. Thalassemia-related variants were identified using third-generation sequencing (TGS). The overall carrier rate of thalassemia in the Buyi population was 22.83% (229/1003). The carrier rates of α-thalassemia, β-thalassemia, and δ-thalassemia were 16.15% (162/1003), 6.68% (67/1003), and 1.20% (12/1003), respectively. The most common α-thalassemia genotype was -α
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