Evidence map›Paper›PMID 41042143›Full record

ArticlePain management2025

Patient reported outcomes following genicular nerve radio frequency ablation for osteoarthritis-related knee pain.

Melissa Schwartz, Komal Luthra, Sophia Salingaros, Ahmed Khawer, Paulina Giacomelli, Ryan Roemmich, Pranamya Suri, Scott Benkovic, Akhil Chhatre

Abstract read
In one paragraph

Article in Pain management, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Melissa SchwartzDepartment of Physical Medicine & Rehabilitation, Johns Hopkins Hospital, Baltimore, MD, USA.
Komal LuthraDepartment of Physical Medicine & Rehabilitation, Johns Hopkins Hospital, Baltimore, MD, USA.ORCID 0000-0002-5500-7598
Sophia SalingarosMedical College, Weil Cornell Medicine, New York, NY, USA.
Ahmed KhawerDepartment of Physical Medicine & Rehabilitation, Johns Hopkins Hospital, Baltimore, MD, USA.
Paulina GiacomelliDepartment of Physical Medicine & Rehabilitation, University of California Irvine, Orange, CA, USA.
Ryan RoemmichDepartment of Physical Medicine & Rehabilitation, Johns Hopkins Hospital, Baltimore, MD, USA.
Pranamya SuriDepartment of Physical Medicine & Rehabilitation, Johns Hopkins Hospital, Baltimore, MD, USA.
Scott BenkovicDepartment of Physical Medicine & Rehabilitation, Johns Hopkins Hospital, Baltimore, MD, USA.
Akhil ChhatreDepartment of Physical Medicine & Rehabilitation, Johns Hopkins Hospital, Baltimore, MD, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionGenicular radiofrequency ablation (RFA) is a minimally invasive treatment for knee pain with variable outcomes reported. This study aimed to evaluate genicular RFA in reducing pain and identify predictors of treatment success.

methodsThis retrospective study included 34 patients who underwent genicular RFA between April 2022 and December 2023. Data on demographics, pre- and post-procedure pain levels, and clinical variables were collected through chart reviews and follow-up surveys. The primary outcome was pain reduction at postoperative follow up. Statistical analyses were conducted to identify predictors of pain outcomes.

resultsRFA led to pain reduction in 24 patients (71%), though only 9 (26%) achieved >50% relief according to IMMPACT criteria. The mean pre-procedure pain score was 7.1 ± 1.4, which decreased to 5.2 ± 2.0 post-procedure. Lower pre-procedure Numeric Rating Score (NRS) was the strongest predictor of success (P < 0.001), while age, BMI, gender, and arthritis severity did not significantly impact outcomes.

conclusionWhile genicular RFA led to pain reduction in a majority of patients, only a subset experienced clinically significant improvement. Pre-procedure pain score was a key predictor of outcomes, suggesting the need for more refined patient selection criteria and further research into optimizing treatment targets.

Indexed as

ArthralgiaOsteoarthritis, KneePain ManagementPatient Reported Outcome MeasuresRadiofrequency AblationAgedFemaleHumansMaleMiddle AgedPain MeasurementRetrospective StudiesTreatment Outcomechronic paingenicularosteoarthritispainRadiofrequency ablation

Identifiers

PMID41042143
PMCPMC12674327

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.