Evidence map›Paper›PMID 41042132›Full record

ArticleEuropean journal of immunology2025

Low-Input Assay for Transposase-Accessible Chromatin Identifies Epigenetic Signatures of Liver Group 1 Innate Lymphoid Cells.

Kevin Schmid, Robin P Schenk, Gabriela M Wiedemann

Abstract read
In one paragraph

Article in European journal of immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Kevin SchmidClinical Department of Internal Medicine II, TUM School of Medicine and Health, TUM University Hospital, Munich, Bavaria, Germany.
Robin P SchenkClinical Department of Internal Medicine II, TUM School of Medicine and Health, TUM University Hospital, Munich, Bavaria, Germany.ORCID 0000-0001-6823-8128
Gabriela M WiedemannClinical Department of Internal Medicine II, TUM School of Medicine and Health, TUM University Hospital, Munich, Bavaria, Germany.

Funding

DFG Emmy Noether program WI 4927/2-1 to GMWElse-Kröner-Fresenius Stiftung grant 2022_EKEA.85 to GMW
6 · The paper itself

Abstract

Assessing chromatin accessibility in rare cell populations within tissue remains a key challenge. To address this, we present a low-input ATAC workflow optimized for liver ILCs. The protocol is validated across cell numbers, Tn5 ratios, and library preparation steps and unveils unique epigenetic features of liver NK cells and ILC1s.

Indexed as

ChromatinEpigenesis, GeneticImmunity, InnateKiller Cells, NaturalLiverLymphocytesTransposasesAnimalsHumansMiceChromatinTransposasesATACchromatin accessibilityepigeneticILC1NK cell

Identifiers

PMID41042132
PMCPMC12493264

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.