Evidence map›Paper›PMID 41042111›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2026

Engineering Dimensional Configuration of Single-Atom S-Cu-S Sites as Reversible Electron Station for Enhanced Peroxidase-Mimicking.

Wenjie Ma, Qian He, Jiancheng Sun, Yiqing Chen, Hongfei Su, Ludan Zhang, Xiao He, Yuguang Wang, Changjian Xie, Zhiyong Zhang and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Wenjie MaCAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety & CAS Center for Excellent in Nanoscience, Institute of High Energy Physics and National Center for Nanoscience and Technology of China, Chinese Academy of Sciences, Beijing, 100049, China.ORCID https://orcid.org/0000-0002-2153-7064
Qian HeSchool of Light Industry and Food Engineering, Guangxi University, Nanning, 530004, China.
Jiancheng SunSchool of Light Industry and Food Engineering, Guangxi University, Nanning, 530004, China.
Yiqing ChenCAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety & CAS Center for Excellent in Nanoscience, Institute of High Energy Physics and National Center for Nanoscience and Technology of China, Chinese Academy of Sciences, Beijing, 100049, China.
Hongfei SuCAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety & CAS Center for Excellent in Nanoscience, Institute of High Energy Physics and National Center for Nanoscience and Technology of China, Chinese Academy of Sciences, Beijing, 100049, China.
Ludan ZhangCenter of Digital Dentistry, Peking University School and Hospital of Stomatology & National Center of Stomatology, Beijing, 100081, China.
Xiao HeCAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety & CAS Center for Excellent in Nanoscience, Institute of High Energy Physics and National Center for Nanoscience and Technology of China, Chinese Academy of Sciences, Beijing, 100049, China.
Yuguang WangCenter of Digital Dentistry, Peking University School and Hospital of Stomatology & National Center of Stomatology, Beijing, 100081, China.
Changjian XieSchool of life Sciences and medicine, Shandong University of Technology, Zibo, 255000, China.
Zhiyong ZhangCAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety & CAS Center for Excellent in Nanoscience, Institute of High Energy Physics and National Center for Nanoscience and Technology of China, Chinese Academy of Sciences, Beijing, 100049, China.
Xin ZhouCollege of Veterinary Medicine, Institute of Comparative Medicine, Yangzhou University, Yangzhou, 225009, China.ORCID https://orcid.org/0000-0003-2515-704X
Yuliang ZhaoCAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety & CAS Center for Excellent in Nanoscience, Institute of High Energy Physics and National Center for Nanoscience and Technology of China, Chinese Academy of Sciences, Beijing, 100049, China.
Wenyan YinCAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety & CAS Center for Excellent in Nanoscience, Institute of High Energy Physics and National Center for Nanoscience and Technology of China, Chinese Academy of Sciences, Beijing, 100049, China.ORCID https://orcid.org/0000-0001-6726-3938

Funding

Municipal Innovation and Technology Cooperation Foundation 24SH21National Key Research and Development Program of China 2021YFA1200904National Key Research and Development Program of China 2022YFA1207600National Natural Science Foundation of China 22175182National Natural Science Foundation of China 52372275Technology Innovation Program of Institute of High Energy Physics Y9545130U2
6 · The paper itself

Abstract

Boosting catalytic activity of single-atom nanozymes (SAzymes) to substitute natural metalloenzymes remains challenging due to the lack of enzyme-like secondary building blocks and proper 3D conformation. Herein, a natural amino acid L-cysteine (L-Cys)-triggered auto-assembly process engineers the spatial positioning of 3D-biomimetic S-Cu-S single-atom catalytic sites and adjacent L-Cys on sheet-like MoS

Indexed as

CopperPeroxidaseCatalysisCatalytic DomainCysteineElectronsHydrogen PeroxideMolybdenumCopperCysteineHydrogen PeroxideMolybdenumPeroxidasebiomimetic catalysisdimensional configurationneighboring metal siteperoxidase‐like activitysingle‐atom nanozymes

Identifiers

PMID41042111
PMCPMC12866787

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.