Evidence map›Paper›PMID 41041912›Full record

ReviewFuture oncology (London, England)2025

Treatment options in hormone-sensitive prostate cancer: targeting the androgen-sensitive pathway.

Cora N Sternberg, Alicia K Morgans

Abstract readReview
In one paragraph

Review in Future oncology (London, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Cora N SternbergEnglander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA.ORCID 0000-0003-3938-2627
Alicia K MorgansDepartment of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This podcast examines how hormone-sensitive prostate cancer (HSPC) is treated, specifically looking at therapies that target the androgen-sensitive pathway. Identification of patients and the clinical rationale for following different treatment pathways is reviewed, including examination of the current treatment options for both metastatic HSPC (mHSPC) and nonmetastatic HSPC, and consideration of barriers that might exist for optimal treatment. The importance of selecting a treatment strategy that offers control of the disease but allows the patient to maintain their functionality and quality of life is discussed, with an emphasis that, for patients with high-risk biochemical recurrence or mHSPC, combination treatment with androgen deprivation therapy and an androgen receptor pathway inhibitor is the standard of care that should be considered unless contraindicated.

Indexed as

Androgen AntagonistsProstatic NeoplasmsAndrogensAntineoplastic Agents, HormonalHumansMaleMolecular Targeted TherapyQuality of LifeReceptors, AndrogenSignal TransductionAndrogen AntagonistsAndrogensAntineoplastic Agents, HormonalReceptors, AndrogenAndrogen receptor pathway inhibitorshormone-sensitive prostate cancerprostate neoplasmsPSMA PET imagingquality of lifetherapeutics

Identifiers

PMID41041912
PMCPMC12707075

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.