Evidence map›Paper›PMID 41041813›Full record

ArticleJournal of microscopy2026

Surface visualisation of bacterial biofilms using neutral atom microscopy.

Nick A von Jeinsen, David J Ward, Matthew Bergin, Sam M Lambrick, David M Williamson, Richard M Langford, Lisa F Dawson, Vibhuti Rana, Sushma Shivaswamy, Xuening Zhou and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of microscopy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Nick A von JeinsenDepartment of Physics, Cavendish Laboratory, University of Cambridge, Cambridge, UK.
David J WardDepartment of Physics, Cavendish Laboratory, University of Cambridge, Cambridge, UK.
Matthew BerginCentre for Organic Electronics, University of Newcastle, Callaghan, New South Wales, Australia.
Sam M LambrickDepartment of Physics, Cavendish Laboratory, University of Cambridge, Cambridge, UK.
David M WilliamsonDepartment of Physics, Cavendish Laboratory, University of Cambridge, Cambridge, UK.
Richard M LangfordDepartment of Physics, Cavendish Laboratory, University of Cambridge, Cambridge, UK.
Lisa F DawsonDepartment of Infection Biology, London School of Hygiene and Tropical Medicine, London, UK.
Vibhuti RanaXBiotech USA Inc., Austin, Texas, USA.
Sushma ShivaswamyXBiotech USA Inc., Austin, Texas, USA.
Xuening ZhouCenter for Nonlinear Dynamics, The University of Texas at Austin, Austin, Texas, USA.
Michelle MikeshDepartment of Physics, The University of Texas at Austin, Austin, Texas, USA.
Vernita D GordonCenter for Nonlinear Dynamics, The University of Texas at Austin, Austin, Texas, USA.
Brendan W WrenDepartment of Infection Biology, London School of Hygiene and Tropical Medicine, London, UK.
Katherine A BrownDepartment of Physics, Cavendish Laboratory, University of Cambridge, Cambridge, UK.
Paul C DastoorDepartment of Physics, Cavendish Laboratory, University of Cambridge, Cambridge, UK.

Funding

Assessing the roles of biofilm structure and mechanics in pathogenic, persistent infectionsR01AI121500 · NIAID · UNIVERSITY OF TEXAS AT AUSTIN · PI GORDON, VERNITA DIANE · 2017 to 2020
$1.5M
National Science Foundation 2150878National Science Foundation 727544NIAID NIH HHS R01 AI121500NIH HHS 1R01AI121500-01A1
6 · The paper itself

Abstract

The scanning helium microscope (SHeM) is a new technology that uses a beam of neutral helium atoms to image surfaces non-destructively and with extreme surface sensitivity. Here, we present the application of the SHeM to image bacterial biofilms. We demonstrate that the SHeM uniquely and natively visualises the surface of the extracellular polymeric substance matrix in the absence of contrast agents and dyes and without inducing radiative damage.

Indexed as

BacteriaBiofilmsMicroscopyHeliumSurface PropertiesHeliumbacterial biofilmsscanning helium microscope

Identifiers

PMID41041813
PMCPMC12746369

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.