Evidence map›Paper›PMID 41041687›Full record

ArticleJournal of veterinary internal medicine

Prognostic Value of Intrarenal Venous Flow Analysis Using Pulsed-Wave Doppler.

Tomoya Morita, Hiroki Terukina, Masahiro Yamasaki

Erratum issuedAbstract read
In one paragraph

Article in Journal of veterinary internal medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Tomoya MoritaLaboratory of Veterinary Small Animal Internal Medicine, Cooperative Department of Veterinary Medicine, Faculty of Veterinary Medicine, Iwate University, Morioka, Japan.ORCID https://orcid.org/0000-0003-2798-5113
Hiroki TerukinaLaboratory of Veterinary Small Animal Internal Medicine, Cooperative Department of Veterinary Medicine, Faculty of Veterinary Medicine, Iwate University, Morioka, Japan.
Masahiro YamasakiLaboratory of Veterinary Small Animal Internal Medicine, Cooperative Department of Veterinary Medicine, Faculty of Veterinary Medicine, Iwate University, Morioka, Japan.ORCID https://orcid.org/0000-0002-9464-0804

Funding

JSPS KAKENHI 20K15657
6 · The paper itself

Abstract

backgroundThe predictive value of intrarenal Doppler ultrasonography (IRD) analysis using pulsed-wave Doppler for survival in dogs with myxomatous mitral valve disease (MMVD) remains unknown. HYPOTHESIS/

objectivesImpaired IRD indices, such as a high venous impedance index (VII), are associated with a short survival time in dogs with MMVD. ANIMALS: Seventy-one client-owned dogs with MMVD.

methodsProspective cohort study. Dogs diagnosed with various stages of MMVD between July 2019 and February 2024 were enrolled. Echocardiography and an IRD analysis were performed. Resistance index and VII were estimated using the following formula: (maximum flow velocity-minimum flow velocity)/maximum flow velocity from renal interlobar arteries and veins, respectively. Intrarenal venous flow waveforms were categorized into continuous and discontinuous patterns. Discontinuous IRVF pattern is defined as a minimum velocity of 0. The primary endpoint was defined as a composite of cardiac- and renal-related death.

resultsDuring the follow-up period, 18 dogs met the primary endpoint. A multivariable Cox proportional hazard analysis adjusted for the Mitral INsufficiency Echocardiographic score and plasma creatinine concentrations identified VII > 0.37 (hazard ratio, at least 4.62; 95% CI, 1.47-14.56) and discontinuous intrarenal venous pattern (hazard ratio, at least 3.62; 95% CI, 1.22-10.73) as an independent predictors of cardiac- and renal-related death. No association between resistance index and outcomes was observed in the multivariable analysis. CONCLUSIONS AND CLINICAL IMPORTANCE: Worse outcomes in dogs with MMVD could be predicted by an intrarenal venous flow analysis.

Indexed as

Dog DiseasesKidneyUltrasonography, Doppler, PulsedAnimalsBlood Flow VelocityDogsFemaleMaleMitral ValvePrognosisProspective Studiescanineintrarenal Dopplermitral regurgitationpulmonary hypertensionvenous impedance index

Identifiers

PMID41041687
PMCPMC12491933

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.