ArticleFrontiers in neurology2025
Analysis of risk factors and their predictive efficacy for postoperative gastrointestinal dysfunction in patients with severe traumatic brain injury.
Article in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Effect of intermittent pneumatic compression on intracranial pressure in postoperative patients with severe traumatic brain injury.The Journal of international medical research · 2026Trial
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7 authors.
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Abstract
Introduction: To investigate the risk factors and their warning effectiveness for postoperative gastrointestinal dysfunction in patients with severe traumatic brain injury (sTBI). Methods: A total of 160 patients with sTBI were divided into the gastrointestinal dysfunction group ( Results: The univariate analysis revealed that intraoperative blood pressure, past medical history, postoperative ICP, enteral nutrition initiation time, postoperative GCS score, neuron specific enolase, S100, IGF-1, and FC were significantly associated with the occurrence of gastrointestinal dysfunction. In addition, multivariate binary logistics regression analysis indicated that IGF-1, postoperative ICP, and FC were significantly associated with postoperative gastrointestinal dysfunction. Among these factors, the ROC curve of IGF-1 demonstrated a higher warning efficacy, which was similar to FC, whereas the ROC curve of ICP showed slightly lower AUC. Discussion: IGF-1, postoperative ICP, and FC are independent factors affecting postoperative gastrointestinal dysfunction in patients with sTBI. Notably, IGF-1 and FC exhibit higher predictive efficacy, while postoperative ICP shows a slightly lower predictive efficacy.
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