Evidence map›Paper›PMID 41041583›Full record

ArticleFrontiers in plant science2025

Development of plant extracts as substrates for untargeted transporter substrate identification in

Christos Theodorou, Victor de-Prado-Parralejo, Deyang Xu, Yoshimasa Todoroki, Louise Svenningsen, Tetsuya Mori, Christoph Crocoll, Masami Yokota Hirai, Hiroshi Tsugawa, Hussam Hassan Nour-Eldin and 1 more

Abstract read
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In one paragraph

Article in Frontiers in plant science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Christos TheodorouDynaMo Center, Department of Plant and Environmental Sciences, University of Copenhagen, Frederiksberg C, Denmark.
Victor de-Prado-ParralejoDynaMo Center, Department of Plant and Environmental Sciences, University of Copenhagen, Frederiksberg C, Denmark.
Deyang XuDynaMo Center, Department of Plant and Environmental Sciences, University of Copenhagen, Frederiksberg C, Denmark.
Yoshimasa TodorokiDepartment of Biotechnology and Life Science, Tokyo University of Agriculture and Technology, Koganei-shi, Tokyo, Japan.
Louise SvenningsenDynaMo Center, Department of Plant and Environmental Sciences, University of Copenhagen, Frederiksberg C, Denmark.
Tetsuya MoriRIKEN Center for Sustainable Resource Science, Yokohama, Kanagawa, Japan.
Christoph CrocollDynaMo Center, Department of Plant and Environmental Sciences, University of Copenhagen, Frederiksberg C, Denmark.
Masami Yokota HiraiRIKEN Center for Sustainable Resource Science, Yokohama, Kanagawa, Japan.
Hiroshi TsugawaDepartment of Biotechnology and Life Science, Tokyo University of Agriculture and Technology, Koganei-shi, Tokyo, Japan.
Hussam Hassan Nour-EldinDynaMo Center, Department of Plant and Environmental Sciences, University of Copenhagen, Frederiksberg C, Denmark.
Barbara Ann HalkierDynaMo Center, Department of Plant and Environmental Sciences, University of Copenhagen, Frederiksberg C, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Amongst the thousands of transport proteins constituting approximately 10% of coding sequences in a genome, only few have an assigned function. Heterologous expression of transporters in combination with the use of plant extracts as complex mixtures of substrates, can be a powerful tool for untargeted identification of plant transporter functionality. In this study, we developed and evaluated four extraction protocols to generate

Indexed as

mass spectrometrynon-targeted metabolomicsoocytesplant extractstransporterstransportomics

Identifiers

PMID41041583
PMCPMC12484206

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.