Evidence map›Paper›PMID 41041508›Full record

ArticlePhysics and imaging in radiation oncology2025

Dosimetric feasibility of stereotactic arrhythmia radioablation for ventricular tachycardia in patients with a subcutaneous implantable cardioverter defibrillator.

Lena Kaestner, Jingyang Xie, Hannah Fanslau, Kerstin Siebenlist, Miriam Eckl, Hans Oppitz, Jens Fleckenstein, Daniel Buergy, Mustafa Kuru, Jürgen Kuschyk and 8 more

Abstract read
In one paragraph

Article in Physics and imaging in radiation oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Lena KaestnerDepartment of Radiation Oncology, University Medical Center Mannheim, Medical Faculty Mannheim, University of Heidelberg/ DKFZ Hector Cancer Institute at the University Medical Center Mannheim, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim, Germany.
Jingyang XieInstitute for Robotics and Cognitive Systems, University of Luebeck, Ratzeburger Allee 160, 23562 Lübeck Germany.
Hannah FanslauDepartment of Radiation Oncology, University Medical Center Mannheim, Medical Faculty Mannheim, University of Heidelberg/ DKFZ Hector Cancer Institute at the University Medical Center Mannheim, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim, Germany.
Kerstin SiebenlistDepartment of Radiation Oncology, University Medical Center Mannheim, Medical Faculty Mannheim, University of Heidelberg/ DKFZ Hector Cancer Institute at the University Medical Center Mannheim, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim, Germany.
Miriam EcklDepartment of Radiation Oncology, University Medical Center Mannheim, Medical Faculty Mannheim, University of Heidelberg/ DKFZ Hector Cancer Institute at the University Medical Center Mannheim, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim, Germany.
Hans OppitzDepartment of Radiation Oncology, University Medical Center Mannheim, Medical Faculty Mannheim, University of Heidelberg/ DKFZ Hector Cancer Institute at the University Medical Center Mannheim, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim, Germany.
Jens FleckensteinDepartment of Radiation Oncology, University Medical Center Mannheim, Medical Faculty Mannheim, University of Heidelberg/ DKFZ Hector Cancer Institute at the University Medical Center Mannheim, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim, Germany.
Daniel BuergyDepartment of Radiation Oncology, University Medical Center Mannheim, Medical Faculty Mannheim, University of Heidelberg/ DKFZ Hector Cancer Institute at the University Medical Center Mannheim, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim, Germany.
Mustafa KuruDepartment of Radiology, University Medical Center Mannheim, University of Heidelberg, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim, Germany.
Jürgen KuschykI. Department of Medicine: Cardiology, Angiology, Hemostaseology and Intensive Care, University Medical Center Mannheim, Medical Faculty Mannheim, University of Heidelberg/ DZHK (German Centre for Cardiovascular Research) Partner Site Mannheim, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim, Germany.
Daniel DürschmiedI. Department of Medicine: Cardiology, Angiology, Hemostaseology and Intensive Care, University Medical Center Mannheim, Medical Faculty Mannheim, University of Heidelberg/ DZHK (German Centre for Cardiovascular Research) Partner Site Mannheim, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim, Germany.
Mathieu KruskaI. Department of Medicine: Cardiology, Angiology, Hemostaseology and Intensive Care, University Medical Center Mannheim, Medical Faculty Mannheim, University of Heidelberg/ DZHK (German Centre for Cardiovascular Research) Partner Site Mannheim, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim, Germany.
David KrugDepartment of Radiation Oncology, University Hospital Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany.
Frank A GiordanoDepartment of Radiation Oncology, University Medical Center Mannheim, Medical Faculty Mannheim, University of Heidelberg/ DKFZ Hector Cancer Institute at the University Medical Center Mannheim, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim, Germany.
Achim SchweikardInstitute for Robotics and Cognitive Systems, University of Luebeck, Ratzeburger Allee 160, 23562 Lübeck Germany.
Oliver BlanckDepartment of Radiation Oncology, University Medical Center Schleswig-Holstein, Arnold-Heller-Straße 3, 24105 Kiel, Germany.
Boris RudicI. Department of Medicine: Cardiology, Angiology, Hemostaseology and Intensive Care, University Medical Center Mannheim, Medical Faculty Mannheim, University of Heidelberg/ DZHK (German Centre for Cardiovascular Research) Partner Site Mannheim, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim, Germany.
Judit Boda-HeggemannDepartment of Radiation Oncology, University Medical Center Mannheim, Medical Faculty Mannheim, University of Heidelberg/ DKFZ Hector Cancer Institute at the University Medical Center Mannheim, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and purpose: Subcutaneous implantable cardioverter defibrillators (S-ICDs) are increasingly used to prevent sudden cardiac death. Due to their placement near the left lateral and apical myocardium, S-ICDs can present technical challenges for stereotactic arrhythmia radioablation (STAR) of ventricular tachycardia. This study aimed to evaluate the feasibility of STAR in patients with S-ICDs. Materials and methods: Previously acquired cardiac computed tomography data from ten S-ICD patients were retrospectively analyzed. Organs at risk, S-ICD components, and hypothetical planning target volumes (PTV) for segments 8 (septal), 11 (lateral), and 17 (apical) were contoured. For each patient and segment, two treatment plans were calculated with a prescribed PTV dose of 25 Gy: one plan sparing the S-ICD from the primary radiotherapy beam ('spared') and one without this constraint ('non-spared'). Results: The S-ICD was successfully spared from the primary beam in 27 out of 30 plans, with Conclusions: The presence of an S-ICD is not a contraindication for STAR, although plan quality may decrease with PTVs in lateral segments. Rare cases with a distance between PTV and S-ICD <4 cm may complicate radiation treatment planning.

Indexed as

Planning studySTAR (stereotactic arrhythmia radioablation)Subcutaneous implantable cardioverter defibrillator

Identifiers

PMID41041508
PMCPMC12486173

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.