ArticleFrontiers in medicine2025
Investigating the role of maternal heart rate variability in the onset of labor.
Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
There are currently no measures to accurately predict the onset of labor at term. Currently, the onset of labor is anticipated based on the estimated due date (EDD), which is derived from the day of the last menstrual period or ultrasound-based anatomical information. However, the EDD is not intended to identify physiological factors which may result in the early onset of labor. Therefore, there is a need to identify potential biomarkers that are associated with the onset of labor to accurately predict the timing of delivery. In this exploratory study, we investigated the associations between maternal RR interval (mRRI), maternal heart rate variability (mHRV) features, and the onset of labor. A total of 37 participants were analyzed, including 25 with Electrohysterogram (EHG)-derived signals (age: 28 ± 5.9 years; gestational age (GA): 34 ± 2.7 weeks) and 12 with non-invasive electrocardiogram (NIFECG)-derived signals (age: 32 ± 4.5 years; GA: 38 ± 1.5 weeks). The association of mHRV with the onset of labor was quantified by calculating correlations with time to delivery, defined as the difference between GA at recording and GA at delivery. Correlation analysis revealed that several standard mHRV indices showed strong associations (
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.