SynthesisFrontiers in medicine2025
Traditional Chinese medicine in the management of diabetic foot ulcers: an overview of meta-analyses.
Synthesis in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
2 citing papers in PubMed.
- Multimodal Bioactive Approaches in Smart Dressings for Diabetic Foot Ulcers.International journal of nanomedicine · 2026Review
- Expert consensus on acupuncture for diabetic foot.American journal of clinical and experimental immunology · 2026Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The global rise in diabetic foot ulcer (DFU) complications necessitates more effective therapeutic strategies. Traditional Chinese Medicine (TCM) has been increasingly explored as a potential adjunctive therapy for DFU management. This umbrella review synthesizes evidence from meta-analyses to evaluate the effectiveness and safety of TCM interventions. Methods: A systematic search of PubMed, Scopus, and Web of Science was conducted through May 2025. Eligible meta-analyses were selected based on predefined criteria, and methodological quality was appraised using the AMSTAR 2 tool. Results: Eleven meta-analyses, encompassing 44 datasets and reporting pooled effect sizes for seven clinical outcomes, were included. The TCM interventions analyzed were both topical and oral. The findings revealed that TCM significantly improved DFU-related outcomes, including ulcer size reduction, shortened healing time (by up to 5.7 days in some trials), increased cure rates (up to a 43% relative improvement), and enhanced overall treatment effectiveness. Notably, longer intervention durations and larger sample sizes were associated with stronger positive effects. Conclusion: This review underscores the therapeutic potential of TCM, particularly topical formulations, in enhancing clinical outcomes and accelerating recovery in patients with diabetic foot ulcers.
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