SynthesisFrontiers in medicine2025
Diagnostic performance of dynamic electrocardiography in the diagnosis of myocardial ischemic attack in coronary heart disease: a systematic review and meta-analysis.
Synthesis in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- The application of coronary CT angiography combined with dynamic electrocardiogram in the diagnosis of myocardial ischemia in coronary heart disease.Frontiers in cardiovascular medicine · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Coronary heart disease (CHD) remains a leading cause of mortality worldwide, highlighting the need for early and accurate diagnosis of myocardial ischemia to improve patient outcomes. Dynamic electrocardiography (ECG) has become a critical diagnostic tool due to its capacity for continuous cardiac electrical activity monitoring. However, existing studies show considerable variation in its diagnostic performance. To establish higher-level evidence, this study systematically evaluates the diagnostic accuracy of dynamic ECG for myocardial ischemic episodes in patients with CHD through a comprehensive systematic review and meta-analysis. Methods: A comprehensive literature search was conducted through May 2025 using PubMed, Embase, Web of Science, Cochrane Library, China National Knowledge Infrastructure, and Wanfang databases. Study quality was assessed using the QUADAS-2 instrument. Diagnostic performance was evaluated using sensitivity, specificity, positive likelihood ratio (PLR), negative likelihood ratio (NLR), diagnostic odds ratio (DOR), and the area under the receiver operating characteristic curve (AUC). Results: The meta-analysis included 24 studies comprising 3,509 participants. The pooled diagnostic performance of dynamic ECG for myocardial ischemia showed a sensitivity of 0.75 (95% CI: 0.70-0.80), specificity of 0.70 (95% CI: 0.64-0.75), PLR of 2.50 (95% CI: 1.99-3.13), NLR of 0.36 (95% CI: 0.28-0.45), DOR of 6.64 (95% CI: 4.55-9.69), and an AUC of 0.79 (95% CI: 0.75-0.82). Subgroup analyses indicated higher diagnostic accuracy in studies involving confirmed CHD cases and those using coronary angiography as the reference standard. Conclusion: Dynamic ECG exhibits moderate diagnostic value for detecting myocardial ischemia in patients with CHD. Its clinical application should be integrated with complementary diagnostic approaches. Further high-quality research is necessary to confirm its diagnostic utility and refine implementation protocols. Systematic review registration: INPLASY202560026.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.