Evidence map›Paper›PMID 41041286›Full record

ArticleRSC advances2025

Identification of potential inhibitors of dihydrofolate reductase (DHFR) through blocking the folate biosynthetic pathway of

Sajal Kumar Halder, Arafin Sultana, Iqrar Ahmad, Md Oliullah Rafi, Ive Sultana, Fatiha Elma, Israt Jahan Ananna, Harun Patel, Mahbubul Kabir Himel, Aparna Shil

Abstract read
In one paragraph

Article in RSC advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Sajal Kumar HalderDepartment of Biochemistry and Molecular Biology, Jahangirnagar University Savar Dhaka 1342 Bangladesh.
Arafin SultanaDepartment of Biochemistry and Molecular Biology, Jahangirnagar University Savar Dhaka 1342 Bangladesh.
Iqrar AhmadDepartment of Pharmaceutical Chemistry, Prof. Ravindra Nikam College of Pharmacy Gondur Dhule 424002 Maharashtra India.
Md Oliullah RafiDepartment of Genetic Engineering and Biotechnology, Jashore University of Science and Technology Jashore 7408 Bangladesh.ORCID https://orcid.org/0000-0002-1707-655X
Ive SultanaResearch Assistant at Padma Bioresearch Dhaka Bangladesh.ORCID https://orcid.org/0000-0002-3439-1615
Fatiha ElmaDepartment of Biochemistry and Molecular Biology, Jahangirnagar University Savar Dhaka 1342 Bangladesh.
Israt Jahan AnannaDepartment of Biochemistry and Molecular Biology, Jahangirnagar University Savar Dhaka 1342 Bangladesh.
Harun PatelDivision of Computer Aided Drug Design, Department of Pharmaceutical Chemistry, R. C. Patel Institute of Pharmaceutical Education and Research Shirpur 425405 Maharashtra India.
Mahbubul Kabir HimelDepartment of Botany, Jahangirnagar University Savar Dhaka 1342 Bangladesh aparna@juniv.edu.
Aparna ShilDepartment of Botany, Jahangirnagar University Savar Dhaka 1342 Bangladesh aparna@juniv.edu.ORCID https://orcid.org/0000-0003-4152-4639

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tuberculosis (TB) has emerged as a leading cause of death due to a single infectious agent-

Identifiers

PMID41041286
PMCPMC12486253

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.