Evidence map›Paper›PMID 41041265›Full record

ArticleJournal of the advanced practitioner in oncology2025

Tumor Treating Fields: An Innovative Therapy for Glioblastoma and Other Solid Tumors.

Jennifer N Serventi, Herbert B Newton

Abstract read
In one paragraph

Article in Journal of the advanced practitioner in oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jennifer N ServentiFrom Wilmot Cancer Institute, University of Rochester, Rochester, New York.
Herbert B NewtonUH Seidman Cancer Center, Cleveland Medical Center, Cleveland, Ohio.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tumor Treating Fields (TTFields) therapy specifically disrupts cellular processes necessary for cancer cell viability and tumor progression through the delivery of electric fields from a portable medical device. Patients with solid tumors such as glioblastoma experience significantly improved overall survival when receiving TTFields therapy concomitant with other standard-of-care therapies. TTFields therapy is also well tolerated and allows patients to maintain their quality of life. It is currently approved for the treatment of newly diagnosed and recurrent glioblastoma, pleural mesothelioma, and metastatic non-small cell lung cancer. Advanced practice providers (APPs), such as nurse practitioners, physician assistants, pharmacists, and other advanced oncology professionals, play key roles in the multidisciplinary team when implementing TTFields therapy. Advanced practice providers with prescribing authority can prescribe TTFields therapy after completing a one-time certification training. During the treatment decision-making process, APPs are poised to have in-depth conversations with patients and caregivers about TTFields therapy to help them grasp key concepts regarding efficacy and safety, how to properly use and integrate the device into their daily lives, cost of therapy, and how to get help using the various patient assistance programs. In addition, APPs play important roles in supporting optimal patient adherence and managing adverse events to ensure improved survival outcomes.

Identifiers

PMID41041265
PMCPMC12487835

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.