Evidence map›Paper›PMID 41041241›Full record

ReviewJournal of family medicine and primary care2025

The science of yawning: Exploring its physiology, evolutionary role, and behavioral impact.

Pinaki Deepak Wani, Mayank Agarwal

Abstract readReview
In one paragraph

Review in Journal of family medicine and primary care, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Pinaki Deepak WaniDepartment of Physiology, AIIMS Raebareli, UP, India.
Mayank AgarwalDepartment of Physiology, AIIMS Raebareli, UP, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Yawning is a ubiquitous physiological phenomenon observed across various species, including humans. Traditionally associated with boredom or drowsiness, yawning encompasses a complex interplay of neurological, physiological, and social factors. This article delves into the multifaceted nature of yawning, examining its evolutionary significance, neurological underpinnings, and physiological functions. The initiation of yawning is primarily regulated by the hypothalamus and brainstem, with neurotransmitters such as dopamine, serotonin, and oxytocin playing critical roles. Anatomically, yawning involves coordinated actions of cranial nerves and muscle groups. The physiological functions of yawning extend beyond mere ventilation, with hypotheses suggesting roles in brain cooling, arousal, and alertness. Additionally, yawning has significant social and communicative implications, particularly through the phenomenon of contagious yawning, which is believed to foster empathy and social bonding. Developmentally, yawning emerges early in fetal life and persists throughout the lifespan, with its frequency and triggers evolving with age. Comparative studies in animals reveal yawning's deep evolutionary roots, linked to thermoregulation and social communication. Clinically, excessive yawning may indicate underlying neurological or systemic conditions, necessitating further investigation. This comprehensive exploration underscores yawning as a complex behavior with significant physiological, neurological, and social dimensions, offering insights into human and animal physiology and social interactions.

Indexed as

Arousalbrain coolingcontagious yawningdopamineempathyhypothalamusthermoregulationyawning

Identifiers

PMID41041241
PMCPMC12488162

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.