Evidence map›Paper›PMID 41041163›Full record

ArticleACG case reports journal2025

Beyond the Bone Marrow: Uncommon Manifestation of Multiple Myeloma-A Case Report of Extramedullary Esophageal Involvement.

Kelly Fan, Maya Mahmoud, Mahmoud Y Madi, Antonio Cheesman Rocca, Wissam Kiwan

Abstract readCase Reports
In one paragraph

Article in ACG case reports journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kelly FanDepartment of Internal Medicine, SSM Health Saint Louis University, St Louis, MO.
Maya MahmoudDepartment of Internal Medicine, SSM Health Saint Louis University, St Louis, MO.
Mahmoud Y MadiDivision of Gastroenterology and Hepatology, The University of Texas at Austin Dell Medical School, Austin, TX, USA.ORCID https://orcid.org/0000-0001-5759-3386
Antonio Cheesman RoccaDivision of Gastroenterology & Hepatology, Department of Internal Medicine, SSM Health Saint Louis University, St Louis, MO.
Wissam KiwanDivision of Gastroenterology & Hepatology, Department of Internal Medicine, SSM Health Saint Louis University, St Louis, MO.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Extramedullary multiple myeloma is an aggressive form of myeloma, with gastrointestinal involvement occurring in less than 5% of cases. We present a 60-year-old man admitted after a syncopal episode. Imaging revealed a large esophageal mass and multiple lytic bone lesions. Biopsy confirmed IgG kappa multiple myeloma without bone marrow involvement. Despite chemotherapy, the disease progressed, and the patient passed away 6 months later. Extramedullary esophageal involvement in the setting of advanced multiple myeloma is rare, with only 2 prior reported cases.

Indexed as

bone marrowesophageal massextramedullary diseasegastrointestinal tractmultiple myeloma

Identifiers

PMID41041163
PMCPMC12487909

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.