Evidence map›Paper›PMID 41041151›Full record

ArticleInternational medical case reports journal2025

Feasibility and Tolerability of Controllable Pulse Parameter Transcranial Magnetic Stimulation in Patients with Painful Diabetic Neuropathy: A Case Series Study.

Jiyeon Park, Stevie D Foglia, Chloe C Drapeau, Perry V Mayer, Harsha Shanthanna, Aimee J Nelson

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in International medical case reports journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jiyeon ParkDepartment of Kinesiology, McMaster University, Hamilton, ON, Canada.ORCID 0009-0006-5027-9769
Stevie D FogliaSchool of Biomedical Engineering, McMaster University, Hamilton, ON, Canada.ORCID 0000-0003-2004-6287
Chloe C DrapeauDepartment of Kinesiology, McMaster University, Hamilton, ON, Canada.
Perry V MayerThe Mayer Institute, Hamilton, ON, Canada.
Harsha ShanthannaDepartment of Anesthesia, McMaster University, Hamilton, ON, Canada.ORCID 0000-0002-4105-4465
Aimee J NelsonDepartment of Kinesiology, McMaster University, Hamilton, ON, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This case series highlights the feasibility and tolerability of using controllable pulse parameter Transcranial Magnetic Stimulation (cTMS) in individuals with painful diabetic neuropathy (pDN). cTMS delivers repetitive monophasic pulses, which allows for greater and longer lasting effects compared to traditional repetitive TMS (rTMS). All participants (N = 2) tolerated 10 sessions of cTMS over a two-week period (five days per week) with no discomfort from the stimulation. They reported no pain from the stimulation despite their heightened pain sensitivity as a result of pDN. The cTMS intervention improved their pain and quality of life as determined through questionnaires evaluating pain, depression, anxiety, and other related measures. Notably, cTMS has never been evaluated in diabetic neuropathy, and our data suggest that it is feasible and tolerable in this clinical population. It further proposes a potential therapeutic treatment option for individuals with pDN.

Indexed as

cTMSmonophasicneuropathic painnon-invasive brain stimulationpDNrTMS

Identifiers

PMID41041151
PMCPMC12484107

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.